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suppressin
calf-thymus hormone with 17-19 amino acid residues; used to treat histiocytosis-X; MW: 1700 daltons;
Networked:
5
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Hormones, Hormone Substitutes, and Hormone Antagonists
Hormones: 80400
Thymus Hormones: 55
suppressin: 5
Experts
1.
Frost, A R
: 1 article (11/2001)
2.
Gary, B D
: 1 article (11/2001)
3.
Grizzle, W E
: 1 article (11/2001)
4.
Manne, U
: 1 article (11/2001)
5.
Oelschlager, D K
: 1 article (11/2001)
6.
Weiss, H L
: 1 article (11/2001)
Related Diseases
1.
Pituitary Neoplasms (Pituitary Adenoma)
01/05/1990 - "
Finally, metabolic labeling studies using a rat pituitary tumor cell line, GH3, showed that suppressin was synthesized de novo and secreted by these cells.
"
07/01/1993 - "
Suppressin (SPN) is a novel polypeptide that is synthesized and secreted by normal rat pituitary cells and a rat pituitary tumor cell line, GH3.
"
2.
Histiocytosis
01/01/1988 - "
Response to treatment with daily intramuscularly administered crude calf thymic extract (Suppressin) in 11 patients with Langerhan's histiocytosis (L.H.) is reported.
"
3.
Thromboembolism
10/04/1969 - "
Puerperal thromboembolism and suppressin of lactation by oestrogen.
"
4.
Neoplasms (Cancer)
11/01/2001 - "
Suppressin (SPN), a novel inhibitor of the entry into the cell cycle, has properties of a tumor suppressor gene; however, its role in the development and progression of a human malignancy is not studied.
"
5.
Adenocarcinoma
11/01/2001 - "
Altered subcellular localization of suppressin, a novel inhibitor of cell-cycle entry, is an independent prognostic factor in colorectal adenocarcinomas.
"
Related Drugs and Biologics
1.
Peptides (Polypeptides)