biphalin

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6 relevant articles (0 outcomes, 1 trials/studies) found for this Bio-Agent

Description: enkephalin dimer; two fragments of Ala(2)-enkephalin are connected by a diamine bridge to form above cpd; structure given in first source

Also Known As:

(Tyr-Ala-Gly-Phe-NH2)2; (tyrosyl-alanyl-glycyl-phenylalaninamide)dimer; D-ENK; D-ENK-O; DALA(2); bis(Tyr-Ala-Gly-PheNH2)hydrazide; bis(tyrosyl-alanyl-glycyl-phenylalaninamide)hydrazide

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins

Proteins: 56522

Nerve Tissue Proteins: 2

Neuropeptides: 3367

Opioid Peptides: 1052

Opioid Peptides: 1052

Enkephalins: 853

biphalin: 6

Opioid Peptides: 1052

Enkephalins: 853

biphalin: 6

Experts

1.	Tang, Jie-Liu: 1 article (03/2008)
2.	Lipkowski, Andrzej W: 1 article (03/2008)
3.	Specter, Steven: 1 article (03/2008)

Related Diseases

1.	Body Weight (Weight, Body) 05/01/1987 - "Short-lasting decrease in rectal temperature in mice after intraperitoneal administration of an enkephalin dimer, the so called double-enkephalin--(Tyr-D-Ala-Gly-Phe-NH)2 (D-ENK-O)--at dose 0.1, 0.5, 1, 2.5, 5, 10 and 20 mg/kg of body weight was observed" 07/20/2001 - "In a cross-dependence study, biphalin did not suppress body weight loss after morphine withdrawal, but successfully suppressed weight loss after pentazocine withdrawal" Get all the results and reference details, order at left...
2.	Weight Loss (Weight Reduction) 07/20/2001 - "In a cross-dependence study, biphalin did not suppress body weight loss after morphine withdrawal, but successfully suppressed weight loss after pentazocine withdrawal" Get all the results and reference details, order at left...
3.	Leukemia 09/01/1998 - "Biphalin, in non-cytotoxic concentrations, suppressed in a dose-dependent fashion the replication of Friend leukemia virus (FLV) in Mus dunni cells as determined using a focus forming assay" 09/01/1998 - "Inhibitory effect of biphalin and AZT on murine Friend leukemia virus infection in vitro." 03/01/2008 - "The role of cytokines, and splenocytes in anti-Friend leukemia virus (FLV) activity of biphalin, a synthetic opioid, and AZT was investigated in vitro" 03/01/2008 - "Molecular assessment of the potential combination therapy of cytokines with biphalin and AZT for Friend leukemia virus infection in vitro." Get all the results and reference details, order at left...
4.	Infection 09/01/1998 - "Inhibitory effect of biphalin and AZT on murine Friend leukemia virus infection in vitro." 03/01/2008 - "Molecular assessment of the potential combination therapy of cytokines with biphalin and AZT for Friend leukemia virus infection in vitro." 03/01/2008 - "This antiviral activity of splenocytes or cytokines combined with chemotherapy, biphalin, and/or AZT, could be used as a complementary therapy to current approaches for retroviral infection and benefit acquired immunodeficiency syndrome (AIDS) patients" Get all the results and reference details, order at left...
5.	Retroviridae Infections (Infection, Retrovirus) 09/01/1998 - "These observations indicate that biphalin possesses anti-retroviral activity in vitro, suggesting that this opioid peptide should be examined further in vivo to determine if it is a candidate for combined therapy with AZT and possibly other drugs for retrovirus infections including the human immunodeficiency virus (HIV)." Get all the results and reference details, order at left...
12 Diseases and 6 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Morphine (MS Contin)
2.	Pentazocine (Talwin)
3.	Enkephalins
4.	Opioid Peptides (Opioid Peptide)
5.	Cytokines
6.	Opioid Receptors (Opioid Receptor)
7.	Naloxone (Narcan)
8.	alanylglycine
8 Drugs and Important Bio-Agents and 5 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Analgesia
2 Therapies and Procedures and 2 more articles analyzed in the Research Interface, order at left...

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