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laminarin sulfate

inhibits vascular smooth muscle cell proliferation in culture; an angiogenesis inhibitor; RN given refers to parent cpd

Also Known As:

laminaran sulfate; laminarin sulfate, sodium salt

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Polysaccharides: 15383
  - laminarin sulfate: 5

Experts

1.	Gong, Tao: 1 article (09/2021)
2.	Huang, Shiqi: 1 article (09/2021)
3.	Li, Yuai: 1 article (09/2021)
4.	Lin, Qing: 1 article (09/2021)
5.	Sun, Xun: 1 article (09/2021)
6.	Zhang, Hanming: 1 article (09/2021)
7.	Zhang, Ling: 1 article (09/2021)
8.	Zhang, Yicong: 1 article (09/2021)
9.	Zhang, Zhirong: 1 article (09/2021)
10.	Baker, Aaron B: 1 article (01/2018)

Related Diseases

1.	Atherosclerosis 09/01/1995 - "These effects of laminarin sulfate may have potential clinical applications in diverse situations such as wound healing, angiogenesis, and atherosclerosis." 01/01/2018 - "Polysaccharides such as fucoidan, laminarin sulfate and ulvan have shown promise in reducing atherosclerosis and its accompanying risk factors in animal models. "
2.	Neoplasm Metastasis (Metastasis) 07/23/2002 - "Cell invasion was inhibited in the presence of laminaran sulfate, a potent inhibitor of heparanase activity and experimental metastasis. " 09/23/2021 - "This is the first time that laminarin sulfate has been used as a carrier to inhibit the expression of heparinase and treat melanoma lung metastasis. " 10/29/1999 - "Inhibition of heparanase activity and tumor metastasis by laminarin sulfate and synthetic phosphorothioate oligodeoxynucleotides." 09/23/2021 - "In this system, laminarin sulfate (LAM) suppresses metastasis by reducing heparinase and protecting the extracellular matrix; the ROS-sensitive polypropylene sulfide (PPS) improves the release of the loaded drug in the tumor microenvironment. "
3.	Melanoma (Melanoma, Malignant) 09/23/2021 - "This is the first time that laminarin sulfate has been used as a carrier to inhibit the expression of heparinase and treat melanoma lung metastasis. " 10/29/1999 - "injection of laminarin sulfate, but not of sodium laminarin, before i.v. inoculation of the melanoma or breast-carcinoma cells inhibited the extent of lung colonization by the tumor cells by 80 to 90%. "
4.	Neoplasms (Cancer) 10/29/1999 - "Inhibition of heparanase activity and tumor metastasis by laminarin sulfate and synthetic phosphorothioate oligodeoxynucleotides." 10/29/1999 - "injection of laminarin sulfate, but not of sodium laminarin, before i.v. inoculation of the melanoma or breast-carcinoma cells inhibited the extent of lung colonization by the tumor cells by 80 to 90%. "
5.	Cerebrovascular Disorders (Cerebrovascular Occlusion) 09/01/1995 - "Laminarin sulfate exhibits about 30% of the anticoagulant activity of heparin and is effective therapeutically in the prevention and treatment of cerebrovascular diseases. "

Related Drugs and Biologics

1.	Polysaccharides (Glycans)
2.	ulvan
3.	fucoidan
4.	heparanase
5.	Heparin Lyase (heparin lyase)
6.	Sulfides (Thioethers)
7.	Sodium
8.	Polypropylenes (Polypropylene)
9.	Oligodeoxyribonucleotides
10.	Heparin (Liquaemin)