|1.||Baden, Daniel G: 3 articles (01/2011 - 01/2008)|
|2.||Holland, Patrick T: 2 articles (07/2012 - 05/2004)|
|3.||Bourdelais, Andrea J: 2 articles (01/2011 - 01/2008)|
|4.||Twiner, Michael J: 2 articles (08/2010 - 10/2007)|
|5.||Wang, Zhihong: 2 articles (08/2010 - 10/2007)|
|6.||Ramsdell, John S: 2 articles (11/2009 - 10/2003)|
|7.||Wanner, Adam: 2 articles (07/2009 - 09/2007)|
|8.||Fleming, Lora E: 2 articles (07/2009 - 09/2007)|
|9.||Bean, Judy A: 2 articles (07/2009 - 09/2007)|
|10.||Reich, Andrew: 2 articles (07/2009 - 09/2007)|
|1.||Human Influenza (Influenza)
01/01/2011 - "The purpose of this study was to examine whether or not repeated brevetoxin inhalation, as may occur during a Florida Red Tide, affects pulmonary responses to influenza A. "
01/01/2011 - "Brevetoxin inhalation alters the pulmonary response to influenza A in the male F344 rat."
01/01/2011 - "Influenza virus was cleared from the lungs over the 7-d period; however, there was significantly more virus remaining in the group 4 lungs compared to group 2. Influenza virus significantly increased interleukins-1α and -6 and monocyte chemotactic protein-1 in lung; brevetoxin exposure significantly enhanced the influenza-induced response. "
01/01/2011 - "Male F344 rats were divided into four groups: (1) sham aerosol/no influenza; (2) sham aerosol/influenza; (3) brevetoxin/no influenza; and (4) brevetoxin/influenza. "
01/01/2011 - "At 7 d, the severity of perivascular and peribronchiolar inflammatory cell infiltrates was greatest in group 4. Bronchiolitis persisted, with low incidence and severity, only in group 4 at d 7. These results suggest that repeated inhalation exposure to brevetoxin may delay virus particle clearance and recovery from influenza A infection in the rat lung."
07/01/2012 - "One naturally contaminated sample of each shellfish matrix, with brevetoxin levels ranging from 0.012 to 9.9 mg/kg, was tested in multiple batches, and the RSDs were similar to those for fortified samples at 0.05 mg/kg. Comparisons with limited data for the neurotoxic shellfish poisoning mouse bioassay for four naturally contaminated shellfish samples showed that the regulatory action limit of 0.8 mg/kg is conservative with respect to the bioassay regulatory limit of 20 mouse units/100 g."
06/28/2011 - "brevis through consumption of shellfish contaminated by accumulated brevetoxins (neurotoxic shellfish poisoning) or from aerosolized brevetoxins in sea spray (reduced respiratory function); however, the reason for brevetoxin production has remained a mystery. "
05/01/2004 - "Confirmation of brevetoxin metabolism in cockle, Austrovenus stutchburyi, and greenshell mussel, Perna canaliculus, associated with New Zealand neurotoxic shellfish poisoning, by controlled exposure to Karenia brevis culture."
07/01/2003 - "Brevetoxin B1 (BTX-B1) was isolated from Austrovenus stutchburyi following the 1992-1993 outbreak of neurotoxic shellfish poisoning (NSP) in New Zealand. "
07/01/2003 - "Implication of brevetoxin B1 and PbTx-3 in neurotoxic shellfish poisoning in New Zealand by isolation and quantitative determination with liquid chromatography-tandem mass spectrometry."
10/01/2007 - "Quantification of brevetoxin in the extracts was determined using four independent methods: receptor binding assay (RBA), radioimmunoassay (RIA), neuroblastoma (N2A) cytotoxicity assay, and liquid chromatography/mass spectrometry (LC/MS). "
09/15/2005 - "Lipophilic toxicity from the marine dinoflagellate Karenia brevisulcata: use of the brevetoxin neuroblastoma assay to assess toxin presence and concentration."
04/24/1989 - "The actions of brevetoxin (PbTX-3) were studied on single, voltage-dependent sodium channels and whole-cell currents from the neuroblastoma x glioma cell line NG108-15. "
06/20/2011 - "Although polycavernoside A analogue 5 evoked a sharp reduction of the cellular metabolism of neuroblastoma cells, gambierol scarcely reduced it, and ciguatoxin, brevetoxin, and gymnocin-A failed to produce any signs of cytotoxicity. "
|5.||Ciguatera Poisoning (Ciguatera)
01/01/2008 - "Considering that brevetoxin and ciguatoxin specifically activate voltage-sensitive Na+ channels through the same binding site, brevenal has therefore a good potential for the treatment of ciguatera. "
11/01/2005 - "The fact that 27 plant extracts were found to exert, in vitro, a protective effect against the action of ciguatoxin and/or brevetoxin, paves the way for finding new active compounds to treat ciguatera fish poisoning, provided these compounds also reverse the effects of sodium channel activators."
|1.||Chemokine CCL2 (Monocyte Chemoattractant Protein 1)
|2.||Sodium Channels (Sodium Channel)
|5.||Biological Markers (Surrogate Marker)
|9.||DNA (Deoxyribonucleic Acid)
|10.||Cod Liver Oil