stavudine triphosphate

shows termination substrate properties in DNA synthesis catalyzed by several different DNA polymerases; also abbreviated d4TTP

Also Known As:

2',3'-dedehydro-2',3'-dideoxythymidine triphosphate; 2',3'-dideoxy-2',3'-dehydrothymidine 5'-triphosphate; 2,3-DDDDTTP; thymidine 5'-(tetrahydrogen triphosphate), 2',3'-didehydro-3'-deoxy-

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Baiget, Montserrat: 3 articles (01/2013 - 04/2010)
2.	Domingo, Pere: 3 articles (01/2013 - 04/2010)
3.	Fernandez, Irene: 3 articles (01/2013 - 04/2010)
4.	Salazar, Juliana: 3 articles (01/2013 - 04/2010)
5.	Vidal, Francesc: 3 articles (01/2013 - 04/2010)
6.	Villarroya, Francesc: 3 articles (01/2013 - 04/2010)
7.	Mateo, Maria Gracia: 2 articles (01/2013 - 04/2010)
8.	Torres, Ferran: 2 articles (01/2013 - 04/2011)
9.	Domingo, Joan C: 2 articles (04/2011 - 04/2010)
10.	Pruvost, Alain: 2 articles (04/2011 - 04/2010)

Related Diseases

1.	Lipodystrophy 01/01/2013 - "Low expression thymidylate synthase (TS) polymorphism has been associated with increased stavudine triphosphate intracellular (d4T-TP) levels and the lipodystrophy syndrome. " 04/01/2011 - "Association of thymidylate synthase gene polymorphisms with stavudine triphosphate intracellular levels and lipodystrophy." 04/01/2010 - "Relationship between HIV/Highly active antiretroviral therapy (HAART)-associated lipodystrophy syndrome and stavudine-triphosphate intracellular levels in patients with stavudine-based antiretroviral regimens."
2.	Body Weight (Weight, Body) 11/01/2018 - "We explored intracellular stavudine triphosphate levels in children receiving a reduced dose of 0.5 to 0.75 mg/kg of body weight twice daily to investigate whether a similar dose optimization can safely be made. "

Related Drugs and Biologics

1.	Thymidylate Synthase
2.	Stavudine (Zerit)

Related Therapies and Procedures

1.	Highly Active Antiretroviral Therapy (HAART)