HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

1,2-dihydro-2,2,4-trimethylquinoline

structure given in first source

Also Known As:

1,2-dihydroTMQ

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - 1,2-dihydro-2,2,4-trimethylquinoline: 1

Related Diseases

1.	Carcinogenesis 02/01/1997 - "NTP Toxicology and Carcinogenesis Studies of 1,2-Dihydro-2,2,4-Trimethylquinoline (CAS No. 147-47-7) in F344/N Rats and B6C3F1 Mice (Dermal Studies) and the Dermal Initiation/Promotion Study in Female Sencar Mice."
2.	Neoplasms (Cancer) 02/01/1997 - "Groups of female SENCAR mice received 1,2-dihydro-2,2,4-trimethylquinoline (greater than 90% pure) during a 1-year dermal initiation/promotion study to determine the tumor initiation or promotion potential of the chemical. " 02/01/1997 - "Pathology Findings: No neoplasms or nonneoplastic lesions were attributed to treatment with 1,2-dihydro-2,2,4-trimethylquinoline. "
3.	Carcinoma (Carcinomatosis) 02/01/1997 - "CONCLUSIONS: Under the conditions of these 2-year dermal studies, there was some evidence of carcinogenic activity of 1,2-dihydro-2,2,4-trimethylquinoline in male F344/N rats, based on increased incidences of renal tubule adenoma and adenoma or carcinoma (combined). "
4.	Adenoma (Adenomas) 02/01/1997 - "CONCLUSIONS: Under the conditions of these 2-year dermal studies, there was some evidence of carcinogenic activity of 1,2-dihydro-2,2,4-trimethylquinoline in male F344/N rats, based on increased incidences of renal tubule adenoma and adenoma or carcinoma (combined). "
5.	Skin Neoplasms (Skin Cancer) 02/01/1997 - "Pathology Findings: No skin neoplasms were attributed to treatment with 1,2-dihydro-2,2,4-trimethylquinoline. "