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beta- 1,3- galactosyl- O- glycosyl- glycoprotein beta-1,6-acetylglucosaminyl transferase

with EC 2.4.1.148 this is called beta6-GlcNAc-transferase B; a key enzyme determining the structure of O-linked glycosylation; Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R; RefSeq NM_001490 (human); NM_010265 (mouse); NM_022276 (rat)
Also Known As:
C2GNT protein, human; C2GlcNAcT-I; C2TF; Core2GnT protein, human; GCNT1 protein, human; Gal3-GalNAc-mucin-6-GlcNAc transferase; Gcnt1 protein, mouse; Gcnt1 protein, rat; UDP-GlcNAc-Gal1-3GalNAc-R-(GlcNAc to GalNAc)-beta1-6GlcNAc transferase; beta-1,6-N-acetylglucosaminyltransferase, human; core 2 GlcNAc transferase; core 2 beta6-GlcNAc-transferase; core 2 beta6-Gn-T protein, human; core 2-N-acetylglucosaminyltransferase; glucosaminyl (N-acetyl) transferase 1, core 2, human; glucosaminyl (N-acetyl) transferase 1, core 2, mouse; glucosaminyl (N-acetyl) transferase 1, core 2, rat
Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Fukuda, Minoru: 1 article (07/2009)
2. Hebbel, Robert P: 1 article (07/2009)
3. Huo, Yuqing: 1 article (07/2009)
4. Kowalska, M Anna: 1 article (07/2009)
5. Marth, Jamey D: 1 article (07/2009)
6. Tang, Rong: 1 article (07/2009)
7. Wang, Huan: 1 article (07/2009)
8. Zhang, Chunxiang: 1 article (07/2009)
9. Zhang, Weiyu: 1 article (07/2009)
10. Zhu, Chuhong: 1 article (07/2009)

Related Diseases

1. Neointima
2. Neoplasms (Cancer)
3. Infections
4. Gastroenteritis
5. Colonic Neoplasms (Colon Cancer)

Related Drugs and Biologics

1. Selectins
2. L-Selectin
3. Complementary DNA (cDNA)
4. Glycosyltransferases
5. Polysaccharides (Glycans)
6. Oligosaccharides
7. Mucins
8. Apolipoproteins E (ApoE)
9. Apolipoproteins
10. P-selectin ligand protein