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(asparaginyl- alanyl- asparaginyl- proline)3

11  relevant articles (0 outcomes, 1 trials/studies) found for this Bio-Agent

Description: 12-amino acid synthetic peptide derived from the repeating amino acid sequence found in the surface circumsporozoite protein of Plasmodium falciparum sporozoites; consists of 3 repeating units of Asn-Ala-Asn-Pro

Also Known As:
(Asn-Ala-Asn-Pro)3; (NANP)3

Bio-Agent Context: Research Results

Related Diseases

1. Malaria
01/01/1988 - "A conserved repeated epitope, (NANP)3, of the circumsporozoite protein of Plasmodium falciparum has been identified previously as a putative target for artificially induced immunity to malaria"
01/01/1989 - "A comparative study of three enzyme-linked immunosorbent assays (ELISAs) that employed different (NANP)n peptides (the synthetic peptides (NANP)3 and (NANP)40 as well as the recombinant peptides R32tet32 and R32LR) was carried out using serum samples from individuals who were living in different malaria-endemic areas"
01/01/1988 - "However, the trend towards increasing susceptibility to clinical malaria in subjects entering the transmission season with lower levels of anti-(NANP)3 antibodies was modest, and combined cross-sectional and longitudinal data indicated that the humoral response to (NANP)3 did not play a major role in the development of immunity to clinical malaria in the population we studied."
10/23/1986 - "falciparum sporozoites in humans living in malaria-endemic areas was measured using as antigen the synthetic peptide (NANP)3, which represents the immunodominant region of the circumsporozoite (CS) protein"
02/15/1993 - "We have characterized the immune response of mice to multiple Ag peptide systems (MAP) containing the immunodominant B cell epitope (NANP)3 and one of three distinct Th epitopes, Th2R, Th3R, and CS.T3, of the C terminal region of the circumsporozoite protein of Plasmodium falciparum, a human malaria parasite"
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2. Falciparum Malaria (Plasmodium falciparum Malaria)
04/29/1993 - "falciparum malaria vaccine candidate consisting of tetanus toxoid coupled to linear (Asn-Ala-Asn-Pro)3 ((NANP)3)"
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3. Reperfusion Injury
4. Ischemia
5. Hepatitis
5 Diseases and 11 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1. Antibodies
2. Immunoglobulin M (IgM)
3. Immunoglobulin G (IgG)
4. Antigens
5. Tetanus Toxoid (Vaccine, Tetanus)
6. Nitroprusside (Sodium Nitroprusside)
7. (asparaginyl- alanyl- asparaginyl- proline)3
8. omega-N-Methylarginine (NG Monomethyl L Arginine)
9. B-Lymphocyte Epitopes (B-Cell Epitope)
10. T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)
20 Drugs and Important Bio-Agents and 11 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1. Ligation
1 Therapies and Procedures and 1 more articles analyzed in the Research Interface, order at left...

Research Interface

 

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