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verbenone

platelet aggregation inhibitor; RN given refers to cpd without isomeric designation

Also Known As:

verbenone, (+-)-isomer; verbenone, (1R)-isomer; verbenone, (1S)-isomer

Networked: 8 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Monoterpenes: 522
      - Bicyclic Monoterpenes
        verbenone: 8
  - Cyclic Hydrocarbons: 97
    - Bridged-Ring Compounds: 1
      - Bridged Bicyclo Compounds
        Bicyclic Monoterpenes
        verbenone: 8

Experts

1.	Kim, Won-Ki: 4 articles (01/2022 - 01/2019)
2.	Hwang, Jong-Ik: 3 articles (01/2022 - 01/2019)
3.	Kim, Dong Hwi: 3 articles (01/2022 - 01/2019)
4.	Pahk, Kisoo: 3 articles (01/2022 - 01/2019)
5.	Joung, Chanmin: 2 articles (01/2022 - 04/2020)
6.	Mander, Sunam: 2 articles (05/2021 - 01/2019)
7.	Yong, Hyo Jeong: 2 articles (05/2021 - 01/2019)
8.	Kim, Eun-Ok: 1 article (01/2022)
9.	Kim, Sungeun: 1 article (01/2022)
10.	Kwon, Hyun Woo: 1 article (01/2022)

Related Diseases

1.	Fibrosis (Cirrhosis) 04/23/2020 - "Here, we examined the therapeutic efficacy of novel CD147 inhibiting verbenone derivative SP-8356 ((1S,5R)-4-(3,4-dihydroxy-5-methoxystyryl)-6,6-dimethylbicyclo[3.1.1]hept-3-en-2-one) on corneal fibrosis. "
2.	Breast Neoplasms (Breast Cancer) 01/01/2023 - "This study highlights a promising avenue for advancing breast cancer treatment using these derivatives, founded on (S)-verbenone, showcasing their distinct potential for inducing apoptosis." 01/01/2023 - "Conclusion: These findings underscore the potential of (S)-verbenone isoxazoline-1,3,4-thiadiazole derivatives for breast cancer therapy due to their remarkable apoptotic activity. " 01/01/2023 - "Background: This study aimed to develop novel isoxazoline-1,3,4-thiadiazole hybrids from (S)-verbenone for potential anticancer treatment, particularly focusing on cytotoxic and apoptotic effects in hormone-sensitive MCF-7 and triple-negative MDA-MB-231 breast cancer cells. " 01/01/2019 - "We evaluated SP-8356, an anti-inflammatory synthetic verbenone derivative, with respect to its regulation of breast cancer cell behavior and cancer progression. "
3.	Liver Neoplasms (Liver Cancer) 05/01/2021 - "In this study, SP-8356, a verbenone derivative with anti-inflammatory activity, was investigated for its effect on the growth and migration of liver cancer cells. "
4.	Neoplasms (Cancer) 05/28/2023 - "SP-8356 (A Verbenone Derivative) Inhibits Proliferation, Suppresses Cell Migration and Invasion and Decreases Tumor Growth of Osteosarcoma: Role of PGC-1α/TFAM and AMPK-Activation." 01/01/2019 - "We evaluated SP-8356, an anti-inflammatory synthetic verbenone derivative, with respect to its regulation of breast cancer cell behavior and cancer progression. "
5.	Non-alcoholic Fatty Liver Disease 01/01/2022 - "Here, we investigate whether SP-1154, a novel synthetic verbenone derivative, can inhibit TGF-β/Smad3 signaling thereby exhibiting a therapeutic effect against obesity-induced inflamed VAT and subsequent NAFLD in high-fat diet-induced mice. "

Related Drugs and Biologics

1.	SP-8356
2.	Hormones (Hormone)
3.	Therapeutic Uses
4.	Indomethacin (Indometacin)
5.	Bradykinin
6.	methyl salicylate (Linsal)

Related Therapies and Procedures

1.	Therapeutics