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RSU 1131
structure given in first source
Also Known As:
1-(2-nitro-1-imidazolyl)-3-(2-methyl-1-aziridinyl)-2-propanol; RSU-1131; 1H-Imidazole-1-ethanol, alpha-((2-methyl-1-aziridinyl)methyl)-2-nitro-
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Nitro Compounds: 66
Nitroimidazoles: 565
Misonidazole: 539
RSU 1131: 1
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Imidazoles: 150
Nitroimidazoles: 565
Misonidazole: 539
RSU 1131: 1
Related Diseases
1.
Hypoxia (Hypoxemia)
10/15/1988 - "
Comparison of the cellular DNA damage induced by these agents leads to the following facts: (1) the yield of ssb induced by these agents is substantially increased under hypoxia, (2) RSU-1069 and RSU-1131 are much more effective than misonidazole, on a concentration basis, at causing strand breakage both under hypoxic and aerobic conditions; and (3) RSU-1069 is more efficient on a concentration basis than RSU-1131 at inducing both ssb and dsb under both conditions.
"
Related Drugs and Biologics
1.
Misonidazole
2.
1- (2- nitro- 1- imidazolyl)- 3- aziridino- 2- propanol
3.
1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)