|1.||Chung, Jing-Gung: 4 articles (08/2012 - 10/2009)|
|2.||Yang, Jai-Sing: 4 articles (08/2012 - 10/2009)|
|3.||Carmona-Gutierrez, Didac: 3 articles (11/2013 - 05/2007)|
|4.||Büttner, Sabrina: 3 articles (11/2013 - 05/2007)|
|5.||Madeo, Frank: 3 articles (11/2013 - 05/2007)|
|6.||Eisenberg, Tobias: 3 articles (11/2013 - 05/2007)|
|7.||Hsia, Te-Chun: 3 articles (01/2011 - 10/2009)|
|8.||Basnakian, Alexei G: 3 articles (01/2010 - 02/2005)|
|9.||Shah, Sudhir V: 3 articles (12/2006 - 11/2004)|
|10.||Tavernarakis, Nektarios: 2 articles (11/2013 - 03/2010)|
|1.||Acute Kidney Injury (Acute Renal Failure)
11/01/2004 - "PPAR-alpha ligand ameliorates acute renal failure by reducing cisplatin-induced increased expression of renal endonuclease G."
11/01/2004 - "Mice subjected to a single intraperitoneal injection of cisplatin developed acute renal failure (ARF) at days 3 and 4. At day 4 after cisplatin injection mRNA, protein levels and enzyme activity of proapoptotic renal endonuclease G (Endo G) were increased compared with saline-treated mice. "
09/01/2011 - "DNaseI activity was dramatically reduced only in kidneys of mice with sever nephritis and was the only nuclease that was down-regulated, whereas six other nucleases (DNaseII1 to 3, caspase-activated DNase, Dnase2a, and endonuclease G) were approximately normally expressed in kidneys, liver, and spleen. "
|3.||Osteosarcoma (Osteogenic Sarcoma)
07/01/2007 - "Caspase-independent death of human osteosarcoma cells by flavonoids is driven by p53-mediated mitochondrial stress and nuclear translocation of AIF and endonuclease G."
01/01/2011 - "In this study, notoriously chemoresistant osteosarcoma (OS) cells (Saos-2, U-2 OS) were substantially susceptible to JCTH-4-induced apoptosis through mitochondrial targeting; JCTH-4 induced collapse of mitochondrial membrane potential (MMP), increased reactive oxygen species (ROS) production in isolated mitochondria, and caused release of apoptosis inducing factor (AIF) and endonuclease G (EndoG) from isolated mitochondria. "
01/01/2007 - "Zoledronic acid activates the DNA S-phase checkpoint and induces osteosarcoma cell death characterized by apoptosis-inducing factor and endonuclease-G translocation independently of p53 and retinoblastoma status."
|4.||Brain Ischemia (Cerebral Ischemia)
09/01/2008 - "In conclusion, this study has identified that Endonuclease G is translocated from the cytoplasm to the nucleus of neurons and expressed with apoptotic-like morphology in the nucleus of astroglia in the thalamic reticular nucleus after global cerebral ischemia."
07/01/2010 - "Here, we compared wild-type and endonuclease G null mice to investigate whether endonuclease G plays a role in the PARP-dependent injury that results from transient focal cerebral ischemia. "
09/01/2008 - "Endonuclease G expression in thalamic reticular nucleus after global cerebral ischemia."
09/23/2005 - "We investigated whether the endonuclease G (endoG) translocated from mitochondria to nucleus after transient focal cerebral ischemia (tFCI), thereby contributed to subsequent DNA fragmentation. "
09/23/2005 - "Early nuclear translocation of endonuclease G and subsequent DNA fragmentation after transient focal cerebral ischemia in mice."
08/01/2009 - "The present study further demonstrates that reactive oxygen species (ROS) were generated in abundance in Jurkat leukemia cells upon AD5-10 stimulation and that ROS accumulation subsequently evoked sustained activation of c-Jun N-terminal kinase (JNK), loss of mitochondrial membrane potential, and release of endonuclease G (Endo G) from mitochondria into the cytosol. "
11/01/2009 - "Aloe-emodin promoted the release of apoptosis-inducing factor (AIF), endonuclease G (Endo G), pro-caspase-9 and cytochrome c from the mitochondria via a loss of the mitochondrial membrane potential (DeltaPsi(m)) which was associated with a increase in the ratio of B-cell lymphoma 2-associated X protein (Bax)/B cell lymphoma/leukemia-2 (Bcl-2) and activation of caspase-9 and -3. The free radical scavenger N-acetylcysteine (NAC) and caspase inhibitors markedly blocked aloe-emodin-induced apoptosis. "
|4.||Reactive Oxygen Species (Oxygen Radicals)
|5.||Apoptosis Inducing Factor
|6.||JNK Mitogen-Activated Protein Kinases
|8.||gamma-Aminobutyric Acid (GABA)
|9.||Cytochromes c (Cytochrome c)
|10.||DNA (Deoxyribonucleic Acid)
|1.||Heterologous Transplantation (Xenotransplantation)