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5,6-dehydrokawain

from Alpinia speciosa rhizoma; RN given for cpd without isomeric designation; structure given in first source

Also Known As:

5,6-dehydrokawain, (E)-isomer

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Pyrones: 35
      - 5,6-dehydrokawain: 4

Experts

1.	Tawata, Shinkichi: 2 articles (01/2016 - 10/2014)
2.	Abubakar, Ibrahim B: 1 article (12/2018)
3.	Abubakar, Ramadan M: 1 article (12/2018)
4.	Etti, Imaobong C: 1 article (12/2018)
5.	Malami, Ibrahim: 1 article (12/2018)
6.	Mshelia, Halilu E: 1 article (12/2018)
7.	Muhammad, Aliyu: 1 article (12/2018)
8.	Waziri, Peter M: 1 article (12/2018)
9.	Ide, Masahiro: 1 article (01/2017)
10.	Koizumi, Keiko: 1 article (01/2017)

Related Diseases

1.	Neoplasms (Cancer) 12/01/2018 - "The results revealed that 5,6-dehydrokawain induced the expression of proangiogenic tumour-derived VEGF of HT-29 cells, which may explain the inability of 5,6-dehydrokawain in suppressing cancer cells proliferation." 01/01/2016 - "Hispidin, a metabolite of 5,6-dehydrokawain from alpinia, inhibited the growth of cancer cells with the IC50 of 25 μM as does artepillin C, the major anti-cancer ingredient in Brazilian green propolis. "
2.	Osteoporosis 01/01/2017 - "These results indicated that novel 5,6-dehydrokawain analogs not only increase osteogenic activity but also inhibit osteoclast differentiation, and could be potential lead compounds for the development of anti-osteoporosis agents."
3.	Obesity 10/15/2014 - "The results showed that hispidin, dihydro-5,6-dehydrokawain (DDK), and 5,6-dehydrokawain (DK) have promising anti-obesity properties. "

Related Drugs and Biologics

1.	hispidin
2.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
3.	Propolis (Bee Bread)
4.	artepillin C
5.	7,8-dihydro-5,6-dehydrokawain