|1.||Zhang, Jing: 5 articles (04/2015 - 05/2012)|
|2.||Lu, Meili: 4 articles (11/2015 - 01/2014)|
|3.||Wang, Hongxin: 4 articles (11/2015 - 01/2014)|
|4.||Chen, Xi: 4 articles (02/2015 - 01/2012)|
|5.||Peng, Li-Hua: 4 articles (02/2015 - 01/2012)|
|6.||Gao, Jian-Qing: 4 articles (02/2015 - 01/2012)|
|7.||Du, Qiang: 4 articles (01/2014 - 07/2008)|
|8.||Li, Min: 4 articles (09/2013 - 03/2009)|
|9.||Zhang, Wei-Dong: 4 articles (07/2006 - 06/2004)|
|10.||Tang, Futian: 3 articles (11/2015 - 01/2015)|
|1.||Cardiovascular Diseases (Cardiovascular Disease)
07/17/2006 - "Astragaloside IV was slowly cleared via hepatic clearance with a systemic clearance (CL) of about 0.004 l/kg/min. Based on the favorable pharmacokinetic properties in both rats and dogs, astragaloside IV warrants further investigation for the prevention of cardiovascular diseases."
07/01/2015 - "Astragaloside IV (AS-IV) is widely used for the treatment of cardiovascular diseases in China. "
01/01/2014 - "Astragaloside IV is widely used for the treatment of cardiovascular diseases in China. "
01/01/2015 - "Astragaloside IV (AsIV) is the major effective component extracted from the Chinese herb Astragalus membranaceus, which has been widely used to treat cardiovascular disease. "
12/05/2012 - "Astragaloside IV (AS-IV) was widely used for the treatment of cardiovascular diseases in China. "
01/01/2008 - "In this study, we investigated whether in cultured cardiomyocytes subjected to hypoxia and reoxygenation (H/R) administration of astragaloside IV during H/R attenuates the myocardial cell injury and prevents changes in Ca2+ handling activities and gene expression of SR Ca2+ pump. "
08/01/2011 - "Taken together, our data collectively reveal that astragaloside IV is a novel regulator of HIF-1α and angiogenesis through the PI3K/Akt pathway in HUVECs that are exposed to hypoxia."
06/01/2007 - "To investigate and compare the protective effects of Astragaloside IV (AST) and Quercetin (QUE) on rat myocardial cells after their exposure to hypoxia, and to determine their dose-effect relationship. "
01/01/2012 - "Astragaloside IV (As-IV) exerts beneficial effects on hypoxia/reoxygenation (H/R)-induced cardiomyocyte injury, possibly through normalization of sarcoplasmic reticulum Ca(2+) ATPase (SERCA2a) function. "
01/01/2012 - "Astragaloside IV alleviates hypoxia/reoxygenation-induced neonatal rat cardiomyocyte injury via the protein kinase a pathway."
04/21/2009 - "Protective effects of astragaloside IV on porcine-serum-induced hepatic fibrosis in rats and in vitro effects on hepatic stellate cells."
09/04/2015 - "In the present study, we examined the effect of Astragaloside IV (AS-IV), a component of the traditional Chinese medicinal plant Astragalus membranaceus, on the processes associated with renal fibrosis in cultured mouse renal fibroblasts treated with TGF-β1. "
09/04/2015 - "Astragaloside IV suppresses transforming growth factor-β1 induced fibrosis of cultured mouse renal fibroblasts via inhibition of the MAPK and NF-κB signaling pathways."
10/01/2014 - "Astragaloside IV inhibits renal tubulointerstitial fibrosis by blocking TGF-β/Smad signaling pathway in vivo and in vitro."
01/01/2014 - "Mechanistically, Astragaloside IV-induced fibrosis reduction may be due to deregulation of Smad 3/Fli-1, the major mediators of the fibrotic response and key molecules for TGF-β signaling. "
|4.||Wounds and Injuries (Trauma)
04/15/2013 - "With the rat full-skin excision model, the in vivo regulation of astragaloside IV-based SLN-gel in the wound stages of re-epithelization, angiogenesis, and extracellular matrix remodeling was investigated. "
04/15/2013 - "The effects of astragaloside IV-enriched SLNs on wound healing were determined using the wound scratch test, and their uptake by skin cells was tested in vitro. "
02/15/2012 - "Astragaloside IV was shown to significantly promote the migration of keratinocytes in wound scratching assay. "
01/01/2012 - "Therapeutic effects of astragaloside IV on myocardial injuries: multi-target identification and network analysis."
08/01/2011 - "Astragaloside IV attenuates impulse noise-induced trauma in guinea pig."
01/01/2014 - "In this study, we aim to determine the protective effects of astragaloside IV on myocardial hypertrophy induced by lipopolysaccharide and to identify their precise molecular and cellular mechanisms. "
12/12/2013 - "To test the hypothesis that Astragaloside IV can ameliorate the myocardial hypertrophy and inflammatory effect induced by β-adrenergic hyperactivity, we carried out in vivo and in vitro experiments. "
12/12/2013 - "The results of these studies indicate that Astragaloside IV has good protective effect on myocardial hypertrophy induced by isoproterenol. "
07/01/2008 - "Furthermore, astragaloside IV treatment markedly inhibited airway remodeling, including subepithelial fibrosis, smooth muscle hypertrophy, and goblet cell hyperplasia. "
12/12/2013 - "Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-кB signaling pathway in isoproterenol-induced myocardial hypertrophy."
|7.||Mitogen-Activated Protein Kinases
|10.||Immunoglobulin E (IgE)
|3.||Chinese Traditional Medicine (Traditional Chinese Medicine)