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4-chlorodiphenyl ether

Also Known As:

4-CDE

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Phenyl Ethers: 8
        Halogenated Diphenyl Ethers: 385
        4-chlorodiphenyl ether: 2
- Ethers: 242
  - Phenyl Ethers: 8
    - Halogenated Diphenyl Ethers: 385
      - 4-chlorodiphenyl ether: 2

Related Diseases

1.	Endometriosis 01/01/1997 - "Stimulating effects of 4-chlorodiphenyl ether on surgically induced endometriosis in the mouse." 10/01/1997 - "The objectives of this study were to evaluate a modified surgical procedure to induce endometriosis and validate the model by comparing the effects of estrogen, 4-chlorodiphenyl ether (4-CDE) as a possible estrogenic contaminant, and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a contaminant with predominantly anti-estrogenic activities, on the growth of endometrial implants. "
2.	Cysts 10/01/1997 - "The diameter of the endometrial cysts in the OVX animals was significantly (p < 0.0001) smaller compared with the intact animals and OVX animals replaced with E2 or 4-CDE. " 01/01/1997 - "In conclusion, the repeated exposure to 4-CDE increased the survival rates of the endometriotic cysts in the ovariectomized mouse, which suggests that 4-CDE mimics estrogen effects on endometriotic tissues because the endometrial tissues are dependent on estrogenic support for survival." 01/01/1997 - "There were significantly more cysts formed (P < 0.05) in the 150 mg/kg/d 4-CDE group compared to the vehicle-treated control (60 vs. 8%), but not compared to the estrone-treated positive control (90 vs. 60%). "

Related Drugs and Biologics

1.	Estrogens (Estrogen)
2.	Polychlorinated Dibenzodioxins (TCDD)
3.	Estrone

Related Therapies and Procedures

1.	Operative Surgical Procedures