01/01/1997 - "Stimulating effects of 4-chlorodiphenyl ether on surgically induced endometriosis in the mouse."
10/01/1997 - "The objectives of this study were to evaluate a modified surgical procedure to induce endometriosis and validate the model by comparing the effects of estrogen, 4-chlorodiphenyl ether (4-CDE) as a possible estrogenic contaminant, and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a contaminant with predominantly anti-estrogenic activities, on the growth of endometrial implants. "
10/01/1997 - "The diameter of the endometrial cysts in the OVX animals was significantly (p < 0.0001) smaller compared with the intact animals and OVX animals replaced with E2 or 4-CDE. "
01/01/1997 - "In conclusion, the repeated exposure to 4-CDE increased the survival rates of the endometriotic cysts in the ovariectomized mouse, which suggests that 4-CDE mimics estrogen effects on endometriotic tissues because the endometrial tissues are dependent on estrogenic support for survival."
01/01/1997 - "There were significantly more cysts formed (P < 0.05) in the 150 mg/kg/d 4-CDE group compared to the vehicle-treated control (60 vs. 8%), but not compared to the estrone-treated positive control (90 vs. 60%). "