HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
alpha-methyl-thiobutyrolactone alpha-ethyl
Also Known As:
alpha-ethyl, alpha-methyl-thiobutyrolactone; alpha-EMTBL
Networked:
3
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Lactones: 1549
4-Butyrolactone: 81
alpha-methyl-thiobutyrolactone alpha-ethyl: 3
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Furans: 85
4-Butyrolactone: 81
alpha-methyl-thiobutyrolactone alpha-ethyl: 3
Related Diseases
1.
Seizures (Absence Seizure)
11/01/1992 - "
alpha-EMTBL, representing a new class of experimental anticonvulsant drugs, prevented all seizures except strychnine (STR)- and aminophylline-induced seizures.
"
01/01/1996 - "
The newly discovered anticonvulsant drug, alpha-ethyl-alpha-methylthio butyrolactone (alpha-EMTBL),is as effective as valproate (VPA) in blocking seizures induced by convulsant compounds and maximal electric shock in adult mice.
"
09/01/1989 - "
Anticonvulsant properties of alpha-ethyl-alpha-methyl-gamma-thiobutyrolactone (alpha-EMTBL) were compared with those of the antiepileptic drugs ethosuximide (ESM) and valproate (VPA) by testing their ability to block seizures in mice caused by maximal electroshock (MES), pentylenetetrazol (PTZ), picrotoxin (PICRO), bicuculline (BIC), methyl-6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate (DMCM), N-methyl-D,L-aspartate (NMDA), aminophylline (AMPH), strychnine (STR), beta-ethyl-beta-methyl-gamma-thiobutyrolactone (beta-EMTBL), and t-butylbicyclophosphorothionate (TBPS).
"
2.
Shock
01/01/1996 - "
The newly discovered anticonvulsant drug, alpha-ethyl-alpha-methylthio butyrolactone (alpha-EMTBL),is as effective as valproate (VPA) in blocking seizures induced by convulsant compounds and maximal electric shock in adult mice.
"
Related Drugs and Biologics
1.
Anticonvulsants (Antiepileptic Drugs)
2.
Valproic Acid (Depakote)
3.
Convulsants
4.
Strychnine
5.
Aminophylline (Carine)
6.
N-Methylaspartate (NMDA)
7.
Picrotoxin
8.
Pentylenetetrazole (Metrazol)
9.
Ethosuximide (Zarontin)
10.
Bicuculline