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alpha-methyl-thiobutyrolactone alpha-ethyl

Also Known As:

alpha-ethyl, alpha-methyl-thiobutyrolactone; alpha-EMTBL

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - 4-Butyrolactone: 81
    - alpha-methyl-thiobutyrolactone alpha-ethyl: 3
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Furans: 85
    - 4-Butyrolactone: 81
      - alpha-methyl-thiobutyrolactone alpha-ethyl: 3

Related Diseases

1.	Seizures (Absence Seizure) 11/01/1992 - "alpha-EMTBL, representing a new class of experimental anticonvulsant drugs, prevented all seizures except strychnine (STR)- and aminophylline-induced seizures. " 01/01/1996 - "The newly discovered anticonvulsant drug, alpha-ethyl-alpha-methylthio butyrolactone (alpha-EMTBL),is as effective as valproate (VPA) in blocking seizures induced by convulsant compounds and maximal electric shock in adult mice. " 09/01/1989 - "Anticonvulsant properties of alpha-ethyl-alpha-methyl-gamma-thiobutyrolactone (alpha-EMTBL) were compared with those of the antiepileptic drugs ethosuximide (ESM) and valproate (VPA) by testing their ability to block seizures in mice caused by maximal electroshock (MES), pentylenetetrazol (PTZ), picrotoxin (PICRO), bicuculline (BIC), methyl-6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate (DMCM), N-methyl-D,L-aspartate (NMDA), aminophylline (AMPH), strychnine (STR), beta-ethyl-beta-methyl-gamma-thiobutyrolactone (beta-EMTBL), and t-butylbicyclophosphorothionate (TBPS). "
2.	Shock 01/01/1996 - "The newly discovered anticonvulsant drug, alpha-ethyl-alpha-methylthio butyrolactone (alpha-EMTBL),is as effective as valproate (VPA) in blocking seizures induced by convulsant compounds and maximal electric shock in adult mice. "

Related Drugs and Biologics

1.	Anticonvulsants (Antiepileptic Drugs)
2.	Valproic Acid (Depakote)
3.	Convulsants
4.	Strychnine
5.	Aminophylline (Carine)
6.	N-Methylaspartate (NMDA)
7.	Picrotoxin
8.	Pentylenetetrazole (Metrazol)
9.	Ethosuximide (Zarontin)
10.	Bicuculline