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N-(3-acetamidopropyl)pyrrolidin-2-one

spermidine metabolite in urine

Also Known As:

acisoga

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - Pyrrolidinones: 162
      - N-(3-acetamidopropyl)pyrrolidin-2-one: 4

Experts

1.	Adamski, Jerzy: 1 article (01/2022)
2.	Arehart, Christopher: 1 article (01/2022)
3.	Artati, Anna: 1 article (01/2022)
4.	Barnes, Kathleen C: 1 article (01/2022)
5.	Brunetti, Tonya: 1 article (01/2022)
6.	Campbell, Monica: 1 article (01/2022)
7.	Daya, Michelle: 1 article (01/2022)
8.	Doenges, Katrina: 1 article (01/2022)
9.	Federici, Massimo: 1 article (01/2022)
10.	Johnson, Randi K: 1 article (01/2022)

Related Diseases

1.	Ovarian Neoplasms (Ovarian Cancer) 11/01/2022 - "Using a deep learning model, a panel consisting of seven cancer-related metabolites [diacetylspermine, diacetylspermidine, N-(3-acetamidopropyl)pyrrolidin-2-one, N-acetylneuraminate, N-acetyl-mannosamine, N-acetyl-lactosamine, and hydroxyisobutyric acid] was developed for distinguishing early-stage ovarian cancer from BPM. "
2.	Neoplasms (Cancer) 11/01/2022 - "Using a deep learning model, a panel consisting of seven cancer-related metabolites [diacetylspermine, diacetylspermidine, N-(3-acetamidopropyl)pyrrolidin-2-one, N-acetylneuraminate, N-acetyl-mannosamine, N-acetyl-lactosamine, and hydroxyisobutyric acid] was developed for distinguishing early-stage ovarian cancer from BPM. "
3.	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/18/1991 - "Increased concentrations of acisoga, relative to N1-acetylspermidine, in urines of patients with non-Hodgkin's lymphoma indicated that this conversion diminishes the sensitivity of N1-acetylspermidine as a marker for (tumour) cell death."
4.	Heart Failure 01/01/2022 - "Our analyses suggest that acisoga may be a valuable biomarker to detect patients with heart failure with reduced ejection fraction."
5.	Asthma (Bronchial Asthma) 01/01/2022 - "We found strong evidence (colocalization posterior probability >75%) for a shared causal variant between 3 metabolites and asthma, including the polyamine acisoga and variants in LPP, and derivative leukotriene B4 and intergenic variants in chr10p14. "

Related Drugs and Biologics

1.	Biomarkers (Surrogate Marker)
2.	Polyamines
3.	Leukotriene B4
4.	Acids
5.	N',N''-diacetylspermine
6.	mannosamine (D-mannosamine)
7.	N-acetyllactosamine