|1.||Lowe, Martin: 5 articles (03/2011 - 08/2006)|
|2.||Ooms, Lisa M: 2 articles (08/2015 - 01/2011)|
|3.||Mitchell, Christina A: 2 articles (08/2015 - 01/2011)|
|4.||Luo, Na: 2 articles (09/2014 - 12/2012)|
|5.||Sun, Yang: 2 articles (09/2014 - 12/2012)|
|6.||Tseng, Hsin-Yi: 2 articles (08/2013 - 01/2013)|
|7.||Jin, Lei: 2 articles (08/2013 - 01/2013)|
|8.||Ye, Yan: 2 articles (08/2013 - 01/2013)|
|9.||Zhang, Lin Jie: 2 articles (08/2013 - 01/2013)|
|10.||Hu, Wang Lai: 2 articles (08/2013 - 01/2013)|
|1.||Oculocerebrorenal Syndrome (Lowe Syndrome)
09/02/2014 - "OCRL, an inositol polyphosphate 5-phosphatase, is mutated in Lowe syndrome. "
10/01/2010 - "Species-specific difference in expression and splice-site choice in Inpp5b, an inositol polyphosphate 5-phosphatase paralogous to the enzyme deficient in Lowe Syndrome."
04/10/2009 - "Mutation of the inositol polyphosphate 5-phosphatase OCRL1 causes the X-linked disorder oculocerebrorenal syndrome of Lowe, characterized by defects in the brain, kidneys, and eyes. "
06/01/2008 - "As an example, inositol-polyphosphate 5-phosphatase OCRL (oculocerebrorenal syndrome of Lowe) bound the greatest number of Rabs (i.e. "
11/15/2007 - "The inositol polyphosphate 5-phosphatase INPP5B is closely related to the Lowe syndrome protein OCRL1, sharing a similar substrate specificity, domain organisation and an ability to compensate for loss of OCRL1 in knockout mice. "
|2.||Melanoma (Melanoma, Malignant)
01/01/2013 - "Here we report that the inositol polyphosphate 5-phosphatase, phosphatidylinositol 4,5-bisphosphate 5-phosphatase, has a tumour suppressive role in melanoma. "
08/01/2013 - "Past studies have shown that the inositol polyphosphate 5-phosphatase, phosphatidylinositol 4,5-bisphosphate 5-phosphatase (PIB5PA), is commonly downregulated or lost in melanomas, which contributes to elevated activation of phosphatidylinositol 3-kinase (PI3K)/Akt in melanoma cells. "
03/01/2011 - "Mutation of the inositol polyphosphate 5-phosphatase OCRL1 results in two disorders in humans, namely Lowe syndrome (characterized by ocular, nervous system, and renal defects) and type 2 Dent disease (in which only the renal symptoms are evident). "
08/01/2015 - "Two genetic subtypes have been described to date: Dent disease 1 is caused by mutations of the CLCN5 gene, coding for the chloride/proton exchanger ClC-5; and Dent disease 2 by mutations of the OCRL gene, coding for the inositol polyphosphate 5-phosphatase OCRL-1. "
|4.||Renal Insufficiency (Renal Failure)
|5.||Hearing Loss (Hearing Impairment)
|2.||Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
|6.||Staphylococcal Protein A (A, Protein)
|7.||Messenger RNA (mRNA)
|8.||Proteins (Proteins, Gene)
|9.||Phosphoric Monoester Hydrolases (Phosphatases)