carbonyl reductase (NADPH)

Subscribe to Selected New Research on carbonyl reductase (NADPH)

39 relevant articles (0 outcomes, 2 trials/studies) found for this Bio-Agent

Description: acts on a wide variety of carbonyl compounds including quinones, aldehydes, ketoaldehydes, daunorubicin, prostaglandins E and F; converts 13,14-dihydro-15keto-PGF2alpha to 13,14-dihydroPGF2alpha

Also Known As:

13,14-dihydroprostaglandin F2alpha synthetase; AKR1C19 protein, mouse; AKR7A5 protein, mouse; NADPH-carbonyl reductase; NADPH-dependent carbonyl reductase; aldo-keto reductase; befunolol reductase; daunorubicin reductase; isatin reductase; monomeric short-chain dehydrogenase-reductase; ovarian carbonyl reductase; succinic semialdehyde reductase AKR7A5, mouse

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1

Enzymes: 24340

Oxidoreductases: 6825

Alcohol Oxidoreductases

carbonyl reductase (NADPH): 39

Experts

1.	Ma, Jun: 2 articles (02/2008 - 11/2007)
2.	Zu, Xuyu: 2 articles (02/2008 - 11/2007)
3.	Cao, Deliang: 2 articles (02/2008 - 11/2007)
4.	Yan, Ruilan: 2 articles (02/2008 - 11/2007)
5.	Breton, Jean: 1 article (05/2008)
6.	Findlay, John B C: 1 article (05/2008)
7.	Keen, Jeffrey N: 1 article (05/2008)
8.	Gage, Matthew C: 1 article (05/2008)
9.	Hay, Alastair W: 1 article (05/2008)
10.	Wild, Christopher P: 1 article (05/2008)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 03/31/2005 - "The alterations of the expression of four genes were confirmed by real-time quantitative RTPCR; and the aldo-keto reductase family 1, member C1 (AKR1C1) enzyme activity was detected in HCV-NS4B transiently transfected HeLa cells and Huh-7, a human hepatoma cell line" 08/01/2001 - "In contrast, members of the aldo-keto reductase superfamily have not been found in Nafenopin-induced hepatomas" 01/01/1999 - "4-Hydroxynonenal metabolism by aldo/keto reductase in hepatoma cells." 02/08/2008 - "Recent studies have demonstrated that aldo-keto reductase family 1 B10 (AKR1B10), a novel protein overexpressed in human hepatocellular carcinoma and non-small cell lung carcinoma, may facilitate cancer cell growth by detoxifying intracellular reactive carbonyls" 11/15/2007 - "Aldo-keto reductase family 1 B10 (AKR1B10), a member of aldo-keto reductase superfamily, is overexpressed in human hepatocellular carcinoma, lung squamous cell carcinoma and lung adenocarcinoma" Get all the results and reference details, order at left...
2.	Neoplasms (Cancer) 12/26/2007 - "AKR1B10 is a human aldo-keto reductase (AKR) found to be elevated in several cancer types and in precancerous lesions" 02/01/2004 - "We found several novel tumor-associated protein variants that represent members of the aldo-keto reductase (AKR) superfamily" 08/01/2001 - "We found several tumor-associated variants that represent members of the aldo-keto reductase superfamily" 11/15/2007 - "Aldo-keto reductase family 1 B10 gene silencing results in growth inhibition of colorectal cancer cells: Implication for cancer intervention." 11/01/2007 - "Aldo-keto reductase family 1, member B10 in uterine carcinomas: a potential risk factor of recurrence after surgical therapy in cervical cancer." Get all the results and reference details, order at left...
3.	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/01/2005 - "Overexpression of the aldo-keto reductase family protein AKR1B10 is highly correlated with smokers' non-small cell lung carcinomas." 07/05/2002 - "In patients with non-small cell lung carcinoma, differential display shows that aldo-keto reductase (AKR1C) transcripts are dramatically overexpressed" 11/01/2007 - "Aldo-keto reductase family 1, member B10 (AKR1B10), an enzyme that converts retinals into retinols is known to detect in non-small cell lung carcinoma (squamous cell- and adeno-carcinomas), but is barely expressed in normal tissues" 02/08/2008 - "Recent studies have demonstrated that aldo-keto reductase family 1 B10 (AKR1B10), a novel protein overexpressed in human hepatocellular carcinoma and non-small cell lung carcinoma, may facilitate cancer cell growth by detoxifying intracellular reactive carbonyls" Get all the results and reference details, order at left...
4.	Diabetes Complications 10/01/2005 - "h-AR belongs to the aldo-keto reductase family and is implicated in diabetic complications" 01/30/2001 - "Since effective inhibition of diabetic complications will require early intervention, it is important to delineate whether AR fulfills a physiological role that cannot be compensated by an alternate aldo-keto reductase" 07/14/2000 - "Aldose reductase (AR), a member of the aldo-keto reductase superfamily, has been implicated in the etiology of secondary diabetic complications" Get all the results and reference details, order at left...
5.	Prostatic Neoplasms (Prostate Cancer) 07/16/2008 - "Members of the aldo-keto reductase (AKR) superfamily have been implicated in prostaglandin (PG) metabolism and prostate cancer" 12/01/2008 - "We measured expression of the HSD3B2 (3beta-hydroxysteroid dehydrogenase type 2), AKR1C3 (aldo-keto reductase family 1 member C3) and SRD5A1 (steroid 5alpha reductase type 1) genes for the respective androgen-synthesizing enzymes in LNCaP, LNCaP-AR and DU-145 human prostate cancer cells" 03/01/2003 - "BACKGROUND: As androgens play an essential role in prostate cancer, we sought to develop a real-time PCR to characterize mRNA expression profiles of human members of the Aldo-Keto Reductase (AKR) 1C gene family, as well as of 5 alpha-steroid reductase Type II (SRD5A2) in prostate cancer samples" Get all the results and reference details, order at left...
26 Diseases and 39 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Enzymes
2.	Messenger RNA (mRNA)
3.	NAD (NADH)
4.	glutathione S-transferase M1
5.	benzoquinone (quinone)
6.	Oxidoreductases
7.	Aldehyde Reductase (Aldose Reductase)
8.	Testosterone 5-alpha-Reductase (Testosterone 5 alpha Reductase)
9.	Proteins (Proteins, Gene)
10.	Phosphopyruvate Hydratase (Enolase)
62 Drugs and Important Bio-Agents and 26 more articles analyzed in the Research Interface, order at left...

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