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CN 100
structure given in first source
Also Known As:
10,11-dihydro-alpha-methyl-10-oxodibenzo(b,f)thiepin-2-acetic acid; CN-100
Networked:
9
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Benzothiepins: 2
CN 100: 9
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzothiepins: 2
CN 100: 9
Related Diseases
1.
Weight Gain
12/01/1986 - "
CN-100 also exerted an evident preventive effect on destruction of foot bone, improved the changes in organ weight, and stimulated weight gain.
"
2.
Edema (Dropsy)
12/01/1986 - "
CN-100 inhibited the sustained edema induced by mustard, but the drug did not interfere with the increase in body weight of rats.
"
12/01/1986 - "
The toxicity of CN-100 was definitely less than that of indometacin, although both drugs were similar in antiinflammatory activity and mode of action on rat paw edema.
"
01/01/1987 - "
CN-100 exerted potent inhibitory effects on carrageenin-induced acute inflammatory edema and adjuvant-induced arthritis.
"
12/01/1986 - "
The main metabolite of CN-100 also had a weak antiplatelet effect, and its antiinflammatory effect on carrageenin edema and UV erythema was apparently weaker than that of CN-100.
"
12/01/1986 - "
The inhibitory effect of CN-100 on carrageenin-induced edema was remarkable and nearly equal to that of indometacin.
"
3.
Inflammation (Inflammations)
12/01/1986 - "
Preventively and therapeutically CN-100 showed potent inhibitory effects on adjuvant primary inflammation and secondary lesion.
"
12/01/1986 - "
Results suggest that CN-100 is an effective drug on not only acute but also subacute and chronic inflammation.
"
4.
Erythema
12/01/1986 - "
The main metabolite of CN-100 also had a weak antiplatelet effect, and its antiinflammatory effect on carrageenin edema and UV erythema was apparently weaker than that of CN-100.
"
12/01/1986 - "
CN-100 exerted a potent inhibitory action on erythema induced by UV irradiation, which was equal to and 3 times stronger than pranoprofen and indometacin in activity, respectively.
"
5.
Rheumatoid Arthritis
04/01/1991 - "
[A long-term evaluation of CN-100 in patients with rheumatoid arthritis].
"
02/01/1991 - "
[A clinical evaluation of CN-100 in patients with rheumatoid arthritis].
"
Related Drugs and Biologics
1.
Indomethacin (Indometacin)
2.
Carrageenan
3.
Acetic Acid (Vinegar)
4.
Serotonin (5 Hydroxytryptamine)
5.
Prostaglandins
6.
Pentobarbital (Nembutal)
7.
Nystatin (Mycostatin)
8.
Diclofenac (SR 38)
9.
Concanavalin A
10.
Bradykinin
Related Therapies and Procedures
1.
Intravenous Administration