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dichloroacetonitrile

by-product of water chlorination; structure given in first source

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Nitriles: 227
  - Acetonitriles: 2
    - dichloroacetonitrile: 5

Experts

1.	Isogawa, Takahiro: 1 article (01/2019)
2.	Naka, Hiroshi: 1 article (01/2019)
3.	Naraoka, Asuka: 1 article (01/2019)
4.	Oishi, Shunsuke: 1 article (01/2019)
5.	Okabe, Hiroyuki: 1 article (01/2019)
6.	Chen, Wei: 1 article (11/2018)
7.	Liu, Jianchao: 1 article (11/2018)
8.	Lu, Guanghua: 1 article (11/2018)
9.	Qin, Donghong: 1 article (11/2018)
10.	Wang, Yonghua: 1 article (11/2018)

Related Diseases

1.	Gram-Negative Bacterial Infections 07/12/2023 - "This study demonstrated that typical carbonaceous (C-) DBPs, trihalomethanes (THMs) and typical nitrogenous (N-) DBPs, dichloroacetonitrile (DCAN), trichloroacetonitrile (TCAN) and trichloronitromethane (TCNM) could be formed during chlorination and chloramination of polymyxin B sulfate (PBS), a common polypeptide antibiotic working against Gram-negative bacterial infections. "
2.	Necrosis 06/01/2000 - "Induction of oxidative stress and TNF-alpha secretion by dichloroacetonitrile, a water disinfectant by-product, as possible mediators of apoptosis or necrosis in a murine macrophage cell line (RAW)."
3.	Hepatocellular Carcinoma (Hepatoma) 11/15/2018 - "The cytotoxicity and genotoxicity as well as the oxidative stress of five HANs, namely chloroacetonitrile (CAN), dichloroacetonitrile (DCAN), trichloroacetonitrile (TCAN), bromoacetonitrile (BAN), and dibromoacetonitrile (DBAN) on a hepatoma cell line (HepG2) were determined by single, binary or ternary exposure. "
4.	Dehydration (Water Stress) 01/01/2019 - "A key to the design of this transfer dehydration catalysis is the identification of an efficient water acceptor, dichloroacetonitrile, that preferentially reacts with amides over other polar functional groups with the aid of the Pd catalyst and makes the desired scheme exergonic, thereby driving the dehydration." 01/01/2019 - "Palladium-catalyzed dehydration of primary amides to nitriles efficiently proceeds under mild, aqueous conditions via the use of dichloroacetonitrile as a water acceptor. "
5.	Aneuploidy (Aneuploid) 10/01/1991 - "Dichloroacetonitrile, a by-product of water chlorination, induces aneuploidy in Drosophila." 10/01/1991 - "In this report we show that dichloroacetonitrile, but not dibromoacetonitrile, is an effective inducer of aneuploidy in oocytes of Drosophila melanogaster. "

Related Drugs and Biologics

1.	trichloroacetonitrile
2.	Trihalomethanes
3.	Polymyxin B (Aerosporin)
4.	Peptides (Polypeptides)
5.	Anti-Bacterial Agents (Antibiotics)
6.	chloropicrin
7.	discoidin-binding polysaccharide
8.	dibromoacetonitrile
9.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
10.	Palladium