hepatoma-derived growth factor

MW 18,000-19,000; structurally related to basic fibroblast growth factor

Also Known As:

HRP-1 (hepatoma-derived growth factor-related protein-1); HRP-2 (hepatoma-derived growth factor-related protein-2); hepatoma-derived growth factor-related protein-1; hepatoma-derived growth factor-related protein-2

Networked: 150 relevant articles (0 outcomes, 11 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Nakamura, Hideji: 16 articles (09/2020 - 11/2002)
2.	Tai, Ming-Hong: 15 articles (12/2020 - 09/2007)
3.	Enomoto, Hirayuki: 13 articles (09/2020 - 11/2002)
4.	Everett, Allen D: 11 articles (01/2022 - 12/2002)
5.	Yoshida, Kenya: 10 articles (02/2006 - 11/2002)
6.	Hu, Tsung-Hui: 8 articles (12/2020 - 10/2003)
7.	Kung, Mei-Lang: 8 articles (12/2020 - 03/2012)
8.	Uyama, Hirokazu: 8 articles (07/2007 - 11/2002)
9.	Liu, Li-Feng: 7 articles (12/2020 - 10/2003)
10.	Okuda, Yorihide: 7 articles (10/2006 - 11/2002)

Related Diseases

1.	Neoplasms (Cancer) 02/01/2009 - "This study investigated the expression and prognostic role of hepatoma-derived growth factor (HDGF) in colorectal stromal tumor. " 01/01/2005 - "Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF)." 01/01/2021 - "Mechanism analysis first showed that the function of NAP1L1 was to recruit hepatoma-derived growth factor (HDGF), an oncogene candidate widely documented in tumors. " 06/13/2020 - "Hepatoma-Derived Growth Factor: An Overview and Its Role as a Potential Therapeutic Target Molecule for Digestive Malignancies." 01/01/2018 - "Hepatoma-derived growth factor (HDGF) is commonly over-expressed and plays critical roles in the development and progression in a variety of cancers. "
2.	Hepatocellular Carcinoma (Hepatoma) 01/01/2009 - "Mechanistic study on growth suppression and apoptosis induction by targeting hepatoma-derived growth factor in human hepatocellular carcinoma HepG2 cells." 11/01/2003 - "The present study investigated the expression of hepatoma-derived growth factor (HDGF) in human hepatocellular carcinoma (HCC) and in the liver during hepatocarcinogenesis in two rodent models. " 09/01/2023 - "Determination of the Possible Target Genes of Hepatoma-derived Growth Factor in Hepatoma Cells." 09/01/2020 - "Hepatoma-derived growth factor (HDGF) is involved in the progression of hepatocellular carcinoma (HCC). " 06/19/2015 - "Hepatoma-Derived Growth Factor: Its Possible Involvement in the Progression of Hepatocellular Carcinoma."
3.	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/01/2011 - "Our previous studies revealed that hepatoma-derived growth factor (HDGF) is highly expressed in non-small cell lung cancer (NSCLC) cells, playing important roles in promoting NSCLC cells growth and invasion. " 11/15/2022 - "To uncover the role of hepatoma-derived growth factor (HDGF) in the interaction between TAMs and non-small cell lung cancer (NSCLC) cells. " 12/18/2020 - "The relationship between hepatoma-derived growth factor and prognosis in non-small cell lung cancer: A systematic review and meta-analysis." 08/20/2007 - "[Expression of hepatoma-derived growth factor and its clinical implication in stage I non-small cell lung cancer]." 01/01/2006 - "Down-regulation of hepatoma-derived growth factor inhibits anchorage-independent growth and invasion of non-small cell lung cancer cells."
4.	Glioma (Gliomas) 01/01/2021 - "miR-345 was downregulated in glioma tissues and cells, and targeted to regulate the expression of hepatoma-derived growth factor (HDGF), while HDGF expression was enhanced in glioma. " 01/01/2019 - "Hepatoma-derived growth factor (HDGF) has been considered as a potential glioma therapeutic target, and its expression level in gliomas is positively related to the malignant grade. " 12/01/2017 - "Hepatoma-derived growth factor functions as an unfavorable prognostic marker of human gliomas." 07/01/2012 - "Downregulation of hepatoma-derived growth factor suppresses the malignant phenotype of U87 human glioma cells." 12/27/2021 - "Immunohistochemistry indicated that NAP1L1 and hepatoma-derived growth factor (HDGF) were enhanced in glioma as compared to the para-tumor tissues. "
5.	Endometrial Neoplasms (Endometrial Cancer) 01/01/2014 - "This study examined the correlation between high nuclear expression of hepatoma-derived growth factor (HDGF) and clinicopathologic data in endometrial carcinoma (EC), including patient survival. " 08/01/2022 - "MicroRNA-873 inhibits the proliferation and invasion of endometrial cancer cells by directly targeting hepatoma-derived growth factor." 08/01/2019 - "MicroRNA-873 inhibits the proliferation and invasion of endometrial cancer cells by directly targeting hepatoma-derived growth factor." 01/01/2019 - "Background: Our previous work determined the correlation between high nuclear expression of hepatoma-derived growth factor (HDGF) and clinicopathological data of endometrial cancer (EC); however, the modulatory mechanisms and biological role of HDGF in EC have not been reported. " 01/01/2019 - "Hepatoma-Derived Growth Factor and DDX5 Promote Carcinogenesis and Progression of Endometrial Cancer by Activating β-Catenin."

Related Drugs and Biologics

1.	Intercellular Signaling Peptides and Proteins (Growth Factors)
2.	Proteins (Proteins, Gene)
3.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
4.	Biomarkers (Surrogate Marker)
5.	Disintegrins
6.	Protein Kinases (Protein Kinase)
7.	Long Noncoding RNA
8.	Heparin (Liquaemin)
9.	Conditioned Culture Media
10.	human AZU1 protein

Related Therapies and Procedures

1.	Adjuvant Chemotherapy
2.	Therapeutics