|1.||Gramosa, N V: 2 articles (12/2002 - 08/2002)|
|2.||Silveira, E R: 2 articles (12/2002 - 08/2002)|
|3.||Ximenes, Naiara Coelho: 1 article (12/2015)|
|4.||Pompeu, Débora Gramosa: 1 article (12/2015)|
|5.||Guimarães, Sergio Botelho: 1 article (12/2015)|
|6.||de Castro Brito, Gerly Anne: 1 article (12/2015)|
|7.||de Morais Carvalho, Krishnamurti: 1 article (12/2015)|
|8.||Gramosa, Nilce Viana: 1 article (12/2015)|
|9.||de Lima Silva, Joaquim José: 1 article (12/2015)|
|10.||Duarte, Antoniella Souza Gomes: 1 article (12/2015)|
01/01/2013 - "The epimer of kaurenoic acid from Croton antisyphiliticus is cytotoxic toward B-16 and HeLa tumor cells through apoptosis induction."
07/01/2011 - "Bicyclooctanoids as well as kaurenoic acid exhibited activity against all human cancer cells while benzofuranoids showed selective activity against HeLa. "
08/01/2002 - "The destruction of sea urchin embryos, the inhibition of tumor cell growth and the hemolysis of mouse and human erythrocytes indicate the potential cytotoxicity of kaurenoic acid."
08/01/2002 - "In this work, we studied the effects of kaurenoic acid, a diterpene isolated from the oleo-resin of Copaifera langsdorffii in developing sea urchin (Lytechinus variegatus) embryos, on tumor cell growth in microculture tetrazolium (MTT) test and on mouse and human erythrocytes in hemolysis assay. "
04/01/2013 - "Moreover, the antineoplastic cytotoxicity for kaurenoic acid and the majority of ent-kaurane derivatives were assessed in vitro against a panel of fourteen cancer cell lines, of which allylic alcohols were shown to be the most active compounds. "
10/11/2011 - "Here, we investigated the effect of kaurenoic acid (ent-kaur-16-en-19-oic acid: KA), a diterpenoid that is extracted from Aralia continentalis Kitagawa root, on inflammation. "
06/15/2011 - "Kaurenoic acid dose-dependently reduced paw swelling up to 34.4% at 5h after induction, demonstrating inhibition in an acute inflammation model. "
12/01/2015 - "Effects of Kaurenoic Acid and Arginine on Random Skin Flap Oxidative Stress, Inflammation, and Cytokines in Rats."
06/15/2011 - "Furthermore, the in vivo anti-inflammatory effect of kaurenoic acid was examined in a carrageenan-induced paw edema model. "
06/15/2011 - "To determine its anti-inflammatory effects, LPS-induced RAW264.7 macrophages were treated with different concentrations of kaurenoic acid and carrageenan-induced paw edema mice model was used in vivo. "
07/20/2010 - "The active constituents of the AcOEt fraction kaurenoic acid, alpha-spinasterol, oleanolic acid and baurenol also inhibited TPA-induced ear edema. "
|4.||Parkinsonian Disorders (Parkinsonism)
|1.||Acetic Acid (Vinegar)
|2.||Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)
|4.||Potassium Channels (Potassium Channel)
|7.||Dimethyl Sulfoxide (DMSO)