|1.||Hypertension (High Blood Pressure)
02/01/1991 - "These results suggest that in vivo administration of mespirenone to Sprague-Dawley rats effectively prevents the aldosterone-induced hypertension."
02/01/1991 - "However, mespirenone given in combination with aldosterone reversed the hypertension caused by aldosterone in a dose-dependent manner. "
02/01/1991 - "The effects of the mineralocorticoid antagonist mespirenone on the development and maintenance of aldosterone-induced hypertension in Sprague-Dawley rats has been studied. "
02/01/1991 - "Effect of a new mineralocorticoid antagonist mespirenone on aldosterone-induced hypertension."