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mespirenone

structure given in first source

Also Known As:

7alpha-acetylthio-15beta,16beta-methylene-3-oxo-17alpha-pregna-1,4-diene-21,17-carbolactone; ZK 94679; ZK-94 679

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - Spironolactone: 3235
    - mespirenone: 1
Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnenes: 1
        Spironolactone: 3235
        mespirenone: 1

Related Diseases

1.

Hypertension (High Blood Pressure)

02/01/1991 - "These results suggest that in vivo administration of mespirenone to Sprague-Dawley rats effectively prevents the aldosterone-induced hypertension."
02/01/1991 - "However, mespirenone given in combination with aldosterone reversed the hypertension caused by aldosterone in a dose-dependent manner. "
02/01/1991 - "The effects of the mineralocorticoid antagonist mespirenone on the development and maintenance of aldosterone-induced hypertension in Sprague-Dawley rats has been studied. "
02/01/1991 - "Effect of a new mineralocorticoid antagonist mespirenone on aldosterone-induced hypertension."

Related Drugs and Biologics

1.	Mineralocorticoid Receptor Antagonists
2.	Aldosterone