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demethylwedelolactone

antihepatotoxic coumestan; structure given in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Coumarins: 826
        demethylwedelolactone: 3
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Coumarins: 826
        demethylwedelolactone: 3

Experts

1.	Chen, Po-Yen: 1 article (06/2021)
2.	To, Kin-Ying: 1 article (06/2021)
3.	Tsai, Yung-Ting: 1 article (06/2021)
4.	Chen, Nai-Fang: 1 article (10/2012)
5.	Chuang, Shien-Kai: 1 article (10/2012)
6.	Lee, Yean-Jang: 1 article (10/2012)
7.	Lin, Wea-Lung: 1 article (10/2012)
8.	Tseng, Tsui-Hwa: 1 article (10/2012)

Related Diseases

1.	Polyploidy 06/17/2021 - "No apparent morphological changes were observed between these polyploid plants and the diploid wild-type (WT) plant, except that larger stomata in leaves were found in all polyploid plants as compared to diploid WT. Ultra-performance liquid chromatography coupled with tandem mass spectrometry was used to quantify the four index compounds (wedelolactone, demethylwedelolactone, luteolin, apigenin) in these polyploid plants, and fluctuating patterns were detected. "
2.	Pneumonia (Pneumonitis) 01/10/2024 - "prostrata (MEEP), the major components of which are wedelolactone (WED) and demethylwedelolactone (DMW), exhibited anti-inflammatory activity in acute asthma models but the effects on lung inflammation and the mechanisms of action of MEEP in a chronic asthma model are not known. "
3.	Neoplasm Metastasis (Metastasis) 10/01/2012 - "Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice."
4.	Breast Neoplasms (Breast Cancer) 10/01/2012 - "Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice."
5.	Asthma (Bronchial Asthma) 01/10/2024 - "prostrata (MEEP), the major components of which are wedelolactone (WED) and demethylwedelolactone (DMW), exhibited anti-inflammatory activity in acute asthma models but the effects on lung inflammation and the mechanisms of action of MEEP in a chronic asthma model are not known. "

Related Drugs and Biologics

1.	wedelolactone
2.	Luteolin
3.	Apigenin