mitometh

less toxic than mitotane; structure given in first source

Also Known As:

1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloropropane; 2,2-DDP; 2,2-dichloro-1-(2-chlorophenyl)-1-(4-chlorophenyl)propane; Benzene, 1-chloro-2-(2,2-dichloro-1-(4-chlorophenyl)propyl)-

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Chlorinated Hydrocarbons: 240
      - Mitotane: 664
        mitometh: 2

Related Diseases

1.	Adrenal Gland Neoplasms (Adrenal Cancer) 01/01/1993 - "This observation prompted us to undertake a comparative study of these two drugs on the basis that Mitometh may be a superior agent for the treatment of adrenal cancer. " 01/01/1993 - "We conclude that Mitometh is not likely to be effective in the therapy of adrenal cancer. "
2.	Adrenocortical Carcinoma 01/01/1987 - "Mitometh represents a potential alternative to Lysodren which should be investigated further for its possible use in the treatment of adrenal cortical carcinoma and Cushing's syndrome."
3.	Necrosis 01/01/1993 - "Despite the lack of adrenalytic activity, Mitometh maintained its toxicity as demonstrated by microscopic evidence of hepatic necrosis and an increase in hepatic enzymes. " 01/01/1993 - "Whereas the adrenal glands of Mitotane-treated dogs showed hemorrhage and necrosis, the Mitometh-treated animals showed no adrenal damage. "
4.	Hemorrhage 01/01/1993 - "Whereas the adrenal glands of Mitotane-treated dogs showed hemorrhage and necrosis, the Mitometh-treated animals showed no adrenal damage. "
5.	Diarrhea 01/01/1987 - "In general the animals treated with Mitometh showed less alopecia, diarrhea, and weakness. "

Related Drugs and Biologics

1.	Mitotane (Lysodren)
2.	Enzymes

Related Therapies and Procedures

1.	Therapeutics