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G-T-XIII

a hemostatic material composed of gelatin, thrombin, and factor XIII

Also Known As:

GT-XIII

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Related Diseases

1.	Hypotension (Low Blood Pressure) 10/01/1990 - "Forty-six sclerotherapy sessions were performed on liver cirrhotics with high-risk esophageal varices using GT XIII, a sclerosant composed of gelatin, thrombin and coagulation factor XIII. GT XIII was effective for the prevention of temporary symptoms and transient hypotension observed in 55 sclerotherapy sessions using thrombin. "
2.	Esophageal and Gastric Varices (Esophageal Varices) 10/01/1990 - "Forty-six sclerotherapy sessions were performed on liver cirrhotics with high-risk esophageal varices using GT XIII, a sclerosant composed of gelatin, thrombin and coagulation factor XIII. GT XIII was effective for the prevention of temporary symptoms and transient hypotension observed in 55 sclerotherapy sessions using thrombin. "
3.	Pleural Effusion (Pleural Effusions) 08/01/1990 - "After removing pleural effusion, fibrinogen solution, anticancer agent and our newly devised compound drug, "G.T.XIII" were intrapleurally instilled to enhance an anticancer fibrin membrane. " 04/01/1989 - "After removing pleural effusion, fibrinogen solution was intrapleurally instilled and then, our newly devised material, G.T.XIII and an anticancer drug, Adriamycin (ADM), were administered as chemosclerosing agents in an attempt to prevent recurrence of the effusion and also to provide locoregional antineoplastic effects. "
4.	Neoplasms (Cancer) 08/01/1989 - "Five different types of anticancer drugs were individually entrapped into fibrin clots using our own material, "G.T.XIII" to provide an "anticancer drug-fibrin clot" for regional cancer chemotherapy. "
5.	Disseminated Intravascular Coagulation 10/01/1990 - "Changes in coagulation tests, similar to those of disseminated intravascular coagulation (DIC), were also reduced in sessions using GT XIII. Urinary kallikrein and kinin excretion significantly increased after the procedure (P less than 0.01), indicating activation of the renal kallikrein-kinin system. "

Related Drugs and Biologics

1.	Thrombin
2.	Sclerosing Solutions (Sclerosing Agents)
3.	Gelatin
4.	Factor XIII (Coagulation Factor XIII)
5.	Solutions
6.	Fibrinogen (Factor I)
7.	Fibrin
8.	Antineoplastic Agents (Antineoplastics)
9.	Tissue Kallikreins (Tissue Kallikrein)
10.	Kinins

Related Therapies and Procedures

1.	Sclerotherapy
2.	Drug Therapy (Chemotherapy)