|1.||Zhong, Zhiyuan: 3 articles (10/2013 - 08/2013)|
|2.||Meng, Fenghua: 3 articles (10/2013 - 08/2013)|
|3.||Deng, Chao: 3 articles (10/2013 - 08/2013)|
|4.||Cheng, Ru: 3 articles (10/2013 - 08/2013)|
|5.||Sun, Huanli: 2 articles (10/2013 - 08/2013)|
|6.||Kataoka, Kazunori: 2 articles (06/2012 - 01/2012)|
|7.||Nishiyama, Nobuhiro: 2 articles (06/2012 - 01/2012)|
|8.||Chen, Fengqian: 1 article (12/2015)|
|9.||Zhang, Jinming: 1 article (12/2015)|
|10.||He, Yao: 1 article (12/2015)|
02/01/2012 - "The cytotoxicity study demonstrated that the Au-PEG-SS-DOX nanoconjugates system efficiently released the anticancer drug DOX and enhanced its cytotoxicity against MDR cancer cells. "
08/10/2013 - "MTT assays revealed that DOX-loaded PEG-SS-PTMBPEC micelles had higher anti-tumor activity than reduction-insensitive controls, with low IC50 of 0.75 and 0.60μg/mL for HeLa and RAW 264.7 cells, respectively, following 48h incubation. "
10/19/2011 - "From the in vitro cytotoxicity test, it was found that CPT-loaded PEG-SS-PBLG micelles showed higher toxicity to SCC7 cancer cells than CPT-loaded PEG-b-PBLG micelles without the disulfide bond. "
08/03/2015 - "Finally, the in vivo studies on NCI-H466 tumor-bearing nude mice demonstrated that the OCT(Phe)-PEG-ss-PTX possessed superior tumor-targeting ability and antitumor activity over mPEG-PTX, OCT(Phe)-PEG-PTX and Taxol, as well as minimal collateral damage. "
08/03/2015 - "Consequently, compared with mPEG-PTX and OCT(Phe)-PEG-PTX, the OCT(Phe)-PEG-ss-PTX exhibited much stronger cyotoxicity and apoptosis-inducing ability against NCI-H446 tumor cells (SSTRs overexpression), whereas a comparable cytotoxicity of these prodrugs was obtained against WI-38 normal cells (no SSTRs expression). "
|2.||Glioblastoma (Glioblastoma Multiforme)
08/01/2013 - "The results of the present study suggest that RGD-PEG-SS-PEI represents a promising candidate for further study in glioblastoma and combined gene therapies."
08/01/2013 - "In comparison with mPEG-PEI/pDNA for gene delivery, the RGD-PEG-SS-PEI/pDNA complex provided improved levels of transfection efficiency and reduced cytotoxicity when tested in U87 cells in vitro, and also enhanced levels of gene expression in the brains of intracranial U87 glioblastoma-bearing mice as demonstrated using dsRed gene transfer and bioimaging in vivo. "
|3.||Hepatocellular Carcinoma (Hepatoma)
12/15/2015 - "Herein, we developed a dual-functional biodegradable micellar system constituted by glycyrrhetinic acid coupling poly(ethylene glycol)-disulfide linkage-poly(lactic-co-glycolic acid) (GA-PEG-SS-PLGA) to achieve both hepatoma-targeting and redox-responsive intracellular drug release. "
10/14/2013 - "The micelles were constructed from PEG-SS-PCL and galactose-PEG-PCL (Gal-PEG-PCL) block copolymers, in which Gal-PEG-PCL was designed with a longer PEG than that in PEG-SS-PCL (6.0 vs 5.0 kDa) to fully expose Gal ligands onto the surface of micelles for effective targeting to hepatocellular carcinoma cells. "
10/15/2013 - "To minimize the side effect of chemotherapy, a novel reduction/pH dual-sensitive drug nanocarrier, based on PEGylated dithiodipropionate dihydrazide (TPH)-modified hyaluronic acid (PEG-SS-HA copolymer), was developed for targeted delivery of doxorubicin (DOX) to hepatocellular carcinoma. "
08/12/2013 - "Hepatoma-targeting reduction-sensitive chimaeric biodegradable polymersomes were designed and developed based on galactose-poly(ethylene glycol)-poly(ε-caprolactone) (Gal-PEG-PCL), PEG-PCL-poly(2-(diethylamino)ethyl methacrylate) (PEG-PCL-PDEA, asymmetric), and PEG-SS-PCL for facile loading and triggered intracellular delivery of proteins. "
|1.||monomethoxypolyethylene glycol (MPEG)
|3.||polyethylene glycol-block-polyaspartic acid
|4.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|5.||fluorescent protein 583
|10.||Ethylene Glycol (Monoethylene Glycol)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)