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epidermal pentapeptide

consists of amino acids pGlu, Glu, Asp, Ser, Gly with pGlu at N-terminal end

Also Known As:

EPP peptide; pGlu-Glu-Asp-Ser-GlyOH; pyroglutamyl-glutamyl-aspartyl-seryl-glycine

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - epidermal pentapeptide: 2
- Amino Acids: 30675
  - Acidic Amino Acids: 44
    - Glutamates: 45
      - Pyrrolidonecarboxylic Acid: 255
        epidermal pentapeptide: 2
  - Cyclic Amino Acids: 3
    - Imino Acids: 11
      - Pyrrolidonecarboxylic Acid: 255
        epidermal pentapeptide: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - Pyrrolidinones: 162
      - Pyrrolidonecarboxylic Acid: 255
        epidermal pentapeptide: 2

Related Diseases

1.

12/01/1993 - "The effect of the physiological epidermal proliferation inhibitory substance (EPP) pGlu-Glu-Asp-Ser-GlyOH on the promotion phase in two-stage carcinogenesis was investigated. "
12/01/1993 - "Moderate enhancement of the promotion phase of skin tumorigenesis in hairless mice by topical pretreatment with a mitosis-inhibiting epidermal pentapeptide."
02/01/1989 - "Enhancement of methylnitrosourea-induced skin tumorigenesis and carcinogenesis in hairless mice by pretreatment with a mitosis-inhibiting epidermal pentapeptide."

Related Drugs and Biologics

1.	Methylnitrosourea (N-Methyl-N-nitrosourea)