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tripterine

isolated from Tripterygium wilfordii; structure given in first source; potent inhibitory activity on both Kir2.1 and ERG1 potassium channels, leading to LONG QT SYNDROME
Also Known As:
celastrol; 3-hydroxy-24-nor-2-oxo-1(10),3,5,7-friedelatetraen-29-oic acid
Networked: 202 relevant articles (19 outcomes, 69 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Uzan, Georges: 8 articles (09/2015 - 01/2010)
2. Peng, Bin: 6 articles (09/2015 - 01/2010)
3. Jeoung, Dooil: 5 articles (08/2015 - 06/2009)
4. Zhang, Denghai: 5 articles (05/2015 - 01/2010)
5. Moudgil, Kamal D: 5 articles (04/2015 - 04/2011)
6. Venkatesha, Shivaprasad H: 5 articles (04/2015 - 04/2011)
7. Yang, Bo: 5 articles (10/2014 - 01/2010)
8. Zhu, Hong: 5 articles (10/2014 - 01/2010)
9. Lu, Wei: 5 articles (01/2014 - 01/2010)
10. Sethi, Gautam: 5 articles (04/2012 - 04/2007)

Related Diseases

1. Neoplasms (Cancer)
2. Insulin Resistance
3. Shock
4. Obesity
5. Colitis

Related Drugs and Biologics

1. Cytokines
2. triptolide
3. Protein Isoforms (Isoforms)
4. Interleukin-10 (Interleukin 10)
5. Antibodies
6. Leptin
7. Quinine (Quinson)
8. Collagen Type IV (Type IV Collagen)
9. Tissue Inhibitor of Metalloproteinase-2
10. Tissue Inhibitor of Metalloproteinase-1

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Chinese Traditional Medicine (Traditional Chinese Medicine)
3. Therapeutics
4. Drug Therapy (Chemotherapy)
5. Radiotherapy