DIAM 4

aziridine derivative of a cyclophosphazene cpd; tested for treatment of lupus diseases; structure given in first source

Also Known As:

1,3,5,7,12-Pentaaza-2,4,6-triphospha(6-PV)spiro(5.6)dodeca-1,3,5-triene, 2,2,4,4-tetrakis(1-aziridinyl)-2,2,4,4-tetrahydro-; DIAM4

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Proteinuria 06/01/1990 - "DIAM4 induces the disappearance of the lymphoproliferation, the increase in C3 levels and the decrease in anti-DNA antibody, immunoglobulin and urea levels, and proteinuria. "
2.	Lupus Nephritis 07/01/1992 - "The usefulness of such a model for in vivo evaluation of immunomodulatory and therapeutic effects of drugs, was investigated by treating mice with DIAM4, a cyclophosphazenic compound known to modulate polyclonal activation of lymphocytes and to prevent mouse lupus nephritis. "

1.	Therapeutic Uses
2.	Urea (Carbamide)
3.	Immunoglobulins (Immunoglobulin)
4.	DNA (Deoxyribonucleic Acid)