|1.||Kalvinsh, Ivars: 18 articles (05/2013 - 08/2002)|
|2.||Dambrova, Maija: 11 articles (01/2014 - 08/2002)|
|3.||Liepinsh, Edgars: 11 articles (01/2014 - 08/2002)|
|4.||Klusa, Vija: 7 articles (03/2014 - 10/2006)|
|5.||Isajevs, Sergejs: 7 articles (05/2013 - 10/2006)|
|6.||Svalbe, Baiba: 6 articles (01/2014 - 08/2009)|
|7.||Pupure, Jolanta: 6 articles (05/2013 - 10/2006)|
|8.||Vilskersts, Reinis: 6 articles (06/2012 - 12/2006)|
|9.||Beitnere, Ulrika: 5 articles (03/2014 - 01/2010)|
|10.||Rumaks, Juris: 5 articles (05/2013 - 10/2006)|
01/01/2006 - "To study efficacy of mildronate in the treatment of elderly patients with cardiac failure (CF). "
06/01/2000 - "We previously reported that MET-88, 3-(2,2,2-trimethylhydrazinium) propionate, improved left ventricular diastolic dysfunction induced by congestive heart failure (CHF) in rats. "
05/03/2000 - "Also, MET-88 improved the myocardial energy state in heart-failure rats. "
05/01/2013 - "The aim of the study was to investigate the influence of metabolic treatment with Mildronat on left and right ventricular function, pulmonary flow and systolic synchrony in patient with heart failure. "
01/01/1999 - "To study quality of life (QL) of patients with chronic heart failure (CHF) and QL changes resultant from mildronate therapy. "
07/01/1991 - "A study is presented of the clinico-hemodynamic efficacy of mildronate in 38 patients with ischemic stroke. "
07/01/1991 - "[The efficacy of the mildronate treatment of patients with ischemic stroke]."
10/01/2013 - "This study is designed to evaluate the efficacy and safety of mildronate injection in treating acute ischemic stroke. "
10/01/2013 - "Efficacy and safety of mildronate for acute ischemic stroke: a randomized, double-blind, active-controlled phase II multicenter trial."
06/01/2014 - "Our previous study showed that cinepazide maleate (CM) was as effective and safe as mildronate in the treatment of acute ischemic stroke in a randomized, double-blind, active-controlled phase II multicenter trial, but underlying mechanism(s) is not well understood. "
08/01/2002 - "Mildronate [3-(2,2,2-trimethylhydrazinium)propionate dihydrate] ameliorates cardiac function during ischemia by modulating myocardial energy metabolism. "
09/01/2009 - "In this study, we aimed to investigate whether mildronate can protect the liver against a 90-min normothermic ischemia/30-min reperfusion-induced mitochondrial dysfunction. "
11/01/2000 - "In this study, we investigated whether MET-88 has cardioprotective effects against cardiac dysfunction induced by ischemia/reperfusion. "
09/01/2009 - "Mildronate pre-treatment of rats at doses of 100 or 200 mg/kg/day for one or two weeks did not prevent ischemia/reperfusion-induced mitochondrial dysfunction and liver injury."
09/01/2009 - "Rats were pre-treated for one or two weeks with mildronate (100 mg/kg/day or 200 mg/kg/day) or Ringer solution and subjected to ischemia/reperfusion.We"
|4.||Hypertension (High Blood Pressure)
01/01/2011 - "None of the tested compounds or their combination influenced high salt intake-induced hypertension, while treatment with mildronate and the combination for 8 weeks significantly decreased resting heart rate by 12% and 10%, respectively. "
01/01/2011 - "In conclusion, our results demonstrate that treatment with a combination of L-carnitine and mildronate is protective against hypertension-induced complications in an experimental model of salt-induced hypertension."
01/01/2011 - "This study was performed to investigate the effects of the administration of L-carnitine or mildronate, an inhibitor of L-carnitine biosynthesis, or their combination on the development of hypertension-related complications in Dahl salt-sensitive (DS) rats fed with a high salt diet. "
01/01/2014 - "To study the effect of sanatorium treatment (ST) using sodium chloride baths and metabolic drug mildronat on the dynamics of the ambulatory blood pressure monitoring (ABPM), markers of endothelial function in children with primary arterial hypertension (PAH). "
|5.||Type 2 Diabetes Mellitus (MODY)
01/01/2007 - "The aim of this open randomized study was to compare the clinical efficacy of mildronate in complex therapy of chronic heart failure (CHF) and basic therapy in patients with CHF and type 2 diabetes mellitus (DM2) during the postinfarction period. "
01/01/2007 - "[The use of mildronate in combined therapy of postinfarction chronic heart failure in patients with type 2 diabetes mellitus]."
01/01/2008 - "To clarify mildronate effects on oxidant stress and tissue oxygen in combined treatment of peripheral (sensomotor) neuropathy in patients with type 2 diabetes mellitus (DM). "
|3.||Cytochromes c (Cytochrome c)
|7.||Fatty Acids (Saturated Fatty Acids)
|10.||Proteins (Proteins, Gene)
|4.||Artificial Heart (Artificial Hearts)