|1.||Miyake, N: 2 articles (03/2000 - 01/2000)|
|2.||Takayanagi, Y: 1 article (03/2000)|
|3.||Fujita, R: 1 article (03/2000)|
|4.||Takayanagi, M: 1 article (03/2000)|
|5.||Ishikawa, M: 1 article (03/2000)|
|6.||Sasaki, K: 1 article (03/2000)|
|7.||Tamura, R: 1 article (01/2000)|
|8.||Nishijo, H: 1 article (01/2000)|
|9.||Ono, T: 1 article (01/2000)|
|10.||Nakada, Y: 1 article (01/2000)|
01/17/2000 - "Ameliorative effects of tamolarizine on place learning impairment induced by transient forebrain ischemia in rats."
12/02/1992 - "The rats in group 2 were continuously infused with NC-1100 0.03 or 0.1 mg/kg per min, starting immediately after bilateral carotid artery occlusion, for the 1 h of ischemia and following 3-h recirculation. "
09/01/1992 - "It is suggested that postischemic treatment with the calcium entry blocker, NC-1100, might protect the brain from the ischemic damage produced in patients suffering from transient ischemia."
01/17/2000 - "In the present study we investigated the effect of (+/-)-1-(3, 4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl) ethanol dihydrochloride (tamolarizine), a calcium entry blocker, on place learning impairment in rats with damage selective to the hippocampal CA1 subfield induced by transient forebrain ischemia. "
|2.||Brain Ischemia (Cerebral Ischemia)
01/17/2000 - "Tamolarizine was administered (40 mg/kg) immediately after 15-min brain ischemia. "
12/02/1992 - "The rats received a bolus injection of 0.2 or 1.0 mg/kg NC-1100 i.v. and 1-h cerebral ischemia was then induced by bilateral carotid artery occlusion (group 1). "
12/02/1992 - "At 1 h cerebral ischemia, brain tissue lactate increased 11.5-, 10.1- and 9.8-fold of the normal control given vehicle or NC-1100, 0.2 and 1.0 mg/kg, respectively. "
03/01/1993 - "The anti-ischemic and anoxic effects of NC-1100, a piperazine type calcium channel blocker, were investigated in various cerebral ischemia and anoxia models in mice, gerbils and guinea pigs. "
|3.||Hypertension (High Blood Pressure)
04/01/1989 - "NC-1100 had no effect on hypertension elicited by carotid sinus reflex and on bradycardia by vagus stimulation. "
06/01/1989 - "These results suggest that NC-1100 may be a drug inducing the increase of GABA in the cerebellum and medulla oblongata following continuous administration, especially in animals having hypertension associated cerebrovascular disorders such as SHR-SP."
|5.||Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain)
|2.||Ethanol (Ethyl Alcohol)
|4.||Calcium Channels (Calcium Channel)
|6.||gamma-Aminobutyric Acid (GABA)