HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

cyclosporin H

non-immunophilin-binding cyclosporin; RN given for (D)-Val

Also Known As:

5-(N-methyl-D-valine)cyclosporine A; CsH cyclosporin; cyclosporine H

Networked: 11 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - Cyclosporins: 35
      - Cyclosporine: 17157
        cyclosporin H: 11
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - Cyclosporins: 35
      - Cyclosporine: 17157
        cyclosporin H: 11

Experts

1.	Dai, Lu-Qi: 1 article (11/2018)
2.	Liu, Lian: 1 article (11/2018)
3.	Wang, Hao: 1 article (11/2018)
4.	Wang, Tao: 1 article (11/2018)
5.	Wen, Fu-Qiang: 1 article (11/2018)
6.	Yuan, Zhi-Cheng: 1 article (11/2018)
7.	Zeng, Ni: 1 article (11/2018)
8.	Zhang, Xue: 1 article (11/2018)
9.	Elbayoumi, Tamer: 1 article (04/2017)
10.	Elgebaly, Salwa A: 1 article (04/2017)

Related Diseases

1.	Pneumonia (Pneumonitis) 11/01/2018 - "Cyclosporin H (CsH), a specific inhibitor of FPR1, inhibited lung inflammation in the ALI models. " 04/01/2017 - "Furthermore, in-vivo treatment by Cyclosporin H in the mouse model of HINI Swine flu influenza infection for 5 days markedly reduced lung inflammation and endothelial cell damage. "
2.	Infections 04/01/2017 - "Furthermore, in-vivo treatment by Cyclosporin H in the mouse model of HINI Swine flu influenza infection for 5 days markedly reduced lung inflammation and endothelial cell damage. " 11/01/2007 - "Antagonists to the FPR, such as cyclosporine H (CsH) and chenodeoxycholic acid, or neutralizing antibodies to KC and MIP-2 were injected either 1 h before or 30 min after infection, and then bronchoalveolar lavage fluids were obtained for quantification of bacteria, leukocytes, and chemokines. " 04/01/2017 - "Cyclosporin H completely blocked neutrophil chemotaxis induced by: (a) the standard formyl peptide, f-MLF, (b) the Staphylococcus aureus bacteria-derived formyl peptide Phenol-soluble modulins, such as PSM3a, plus(c) the host-derived Nourin released by: (1) cultured epithelial cells infected with the PR8 HINI influenza virus for 6.to 24 hours, (2),Nourin detected in the serum of mouse model of HINI Swine flu influenza infection for 6 hours , along with (3) Nourin detected in plasma samples collected from severe and moderate influenza pa- tients. "
3.	Carcinogenesis 01/01/2023 - "Pharmacological inhibition of Fpr1 by cyclosporin H also tended to increase intestinal oncogenesis in mice bearing the ApcMin mutation, and this effect was reversed by the anti-inflammatory drug sulindac. "
4.	Wounds and Injuries (Trauma) 03/01/2011 - "Using human Beas2B lung epithelial cells grown to confluency and subjected to linear scratch injury, it was found that mitochondrial antigens enhanced epithelial wound closure, and this phenomenon was inhibited by cyclosporin H, a selective inhibitor of FPR. "
5.	Pain (Aches) 04/01/2009 - "The FPR antagonists Boc-FLFLF and cyclosporine H reduced opioid peptide release in vitro and increased inflammatory pain in vivo while TLR 2/4 did not appear to be involved. "

Related Drugs and Biologics

1.	Cyclosporine (Ciclosporin)
2.	Neutralizing Antibodies
3.	Phenol (Carbolic Acid)
4.	Chemokines
5.	Opioid Peptides (Opioid Peptide)
6.	Tacrolimus (Prograf)
7.	Cytokines
8.	Biomarkers (Surrogate Marker)
9.	Sulindac (Copal)
10.	Phorbol Esters

Related Therapies and Procedures

1.	Therapeutics