N- formylmethionyl- leucyl- phenylalanyl- lysine

Also Known As:

f-Met-Leu-Phe-Lys; fMLFK; fMLPL

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Sulfur Amino Acids: 221
    - Methionine: 6648
      - N-Formylmethionine: 14
        N-Formylmethionine Leucyl-Phenylalanine: 266
        N-formylmethionyl-leucyl-phenylalanyl-lysine: 5
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - N-Formylmethionine Leucyl-Phenylalanine: 266
      - N-formylmethionyl-leucyl-phenylalanyl-lysine: 5
- Amino Acids: 30675
Biological Factors: 2472
- Chemotactic Factors: 3762
  - N-Formylmethionine Leucyl-Phenylalanine: 266
    - N-formylmethionyl-leucyl-phenylalanyl-lysine: 5

Experts

1.	Carter, Edward A: 1 article (09/2002)
2.	Fernandez-Del Castillo, Carlos: 1 article (09/2002)
3.	Fischman, Alan J: 1 article (09/2002)
4.	Hartwig, Werner: 1 article (09/2002)
5.	Jimenez, Ramon E: 1 article (09/2002)
6.	Jones, Rosemary: 1 article (09/2002)
7.	Warshaw, Andrew L: 1 article (09/2002)

Related Diseases

1.	Infections 08/01/1997 - "fMLFK-HYNIC is retained in both acute infection and sterile inflammation by means of specific receptor binding if sufficient cellular infiltration is present." 04/01/1998 - "In the present study, the potential of two species of interleukin 1 (IL-1), IL-1alpha and IL-1beta, the IL-1 receptor antagonist (IL-1ra) and the synthetic chemotactic peptide N-formyl-methionyl-leucyl-phenylalanyl-lysine (fMLFK) were directly compared in a rabbit model of infection. "
2.	Pancreatitis 09/01/2002 - "Lung myeloperoxidase activity, 18FDG, and peripheral white blood cells all significantly increased in both mild and severe pancreatitis, but lung fMLFK only increased in severe pancreatitis. " 08/01/1999 - "Uptake of the (99m)Tc-labeled nicotinyl hydrazine-derivatized chemotactic peptide analog fMLFK-HYNIC was measured in blood, pancreas, lung, and muscle specimens in rats with edematous or necrotizing pancreatitis and was compared with neutrophil sequestration assessed by myeloperoxidase activity and histology. " 08/01/1999 - "We used two well-established models of acute pancreatitis to quantitate the binding of the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine-lysine (fMLFK) to leukocytes and its correlation to degree of organ inflammation. "
3.	Inflammation (Inflammations) 08/01/1997 - "fMLFK-HYNIC is retained in both acute infection and sterile inflammation by means of specific receptor binding if sufficient cellular infiltration is present." 08/01/1999 - "We used two well-established models of acute pancreatitis to quantitate the binding of the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine-lysine (fMLFK) to leukocytes and its correlation to degree of organ inflammation. "
4.	Chronic Kidney Failure (Chronic Renal Failure) 01/01/1987 - "In contrast, peripheral PMN and monocytes from chronic renal failure patients on HD showed no difference in C5a, casein or fMLPL receptors during the course of HD as compared to the predialysis period. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Lysine (L-Lysine)
3.	Interleukin-1 Receptors (Interleukin 1 Receptor)
4.	Interleukin-1 (Interleukin 1)
5.	Peroxidase (Myeloperoxidase)
6.	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)
7.	N-Formylmethionine Leucyl-Phenylalanine
8.	Caseins (Casein)
9.	hydrazine (hydrazine dihydrochloride)