|1.||Drayton, Josephine: 1 article (11/2014)|
|2.||Bai, Xiumei: 1 article (11/2014)|
|3.||Odle, Jack: 1 article (11/2014)|
|4.||Lin, Xi: 1 article (11/2014)|
|5.||Ji, Cheng: 1 article (11/2014)|
|6.||Liu, Yulan: 1 article (11/2014)|
|7.||Mandal, Suvra: 1 article (07/2014)|
|8.||Bhattacharjee, Pushpak: 1 article (07/2014)|
|9.||Kar, Manoj: 1 article (07/2014)|
|10.||Bhattacharya, Sourav: 1 article (07/2014)|
|1.||Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)
01/24/1992 - "Erucic acid (C22:l fatty acid) has been found to be useful in the treatment of adrenoleukodystrophy (ALD). "
11/01/1989 - "We investigated the biochemical and clinical efficacy of dietary erucic acid (C22:1) therapy for X-linked adrenoleukodystrophy (ALD). "
05/01/2008 - "Because X-linked adrenoleukodystrophy is treated using erucic acid (22:1n-9), we assessed its metabolism in rat liver and heart following infusion of [14-(14)C]22:1n-9 (170 Ci/kg) under steady-state-like conditions. "
04/01/1996 - "Effect of erucic acid on platelets in patients with adrenoleukodystrophy."
11/01/1994 - "Ten Japanese boys with childhood adrenoleukodystrophy (ALD), one adult patient with adrenomyeloneuropathy (AMN), and two presymptomatic ALD boys were treated with dietary erucic acid (C22:1) for more than 12 months; except in a case of childhood ALD patient who died 7 months after beginning erucic acid therapy. "
01/01/1978 - "Preliminary studies at our institute indicate lipidosis in the heart both in rats fed RSO and HMO, containing equivalent amounts of erucic acid and erucic acid isomers respectively. "
06/15/2014 - "Foodstuff with a high content of erucic acid is considered undesirable for human consumption because it has been linked to myocardial lipidosis and heart lesions in laboratory rats. "
08/01/1992 - "Effects of dietary saturated fat on erucic acid induced myocardial lipidosis in rats."
07/01/1983 - "The acute lipidosis was reversible with either continued feeding of erucic acid for several weeks or conversion to a normal diet. "
07/01/1983 - "Induction of a reversible cardiac lipidosis by a dietary long-chain fatty acid (erucic acid). "
|3.||Demyelinating Diseases (Demyelinating Disease)
01/01/1998 - "We conclude that the thrombocytopenia in AMN patients using Lorenzo'soil is associated with circulating platelets that have an increased erucic acid content, size and activation status. "
02/01/1995 - "Profound thrombocytopenia complicating dietary erucic acid therapy for adrenoleukodystrophy."
10/01/1993 - "Thrombocytopenia induced by erucic acid therapy in patients with X-linked adrenoleukodystrophy."
05/01/1994 - "Thrombocytopenia, hepatic transaminase abnormalities, anemia and leukopenia developed during the subsequent course of therapy with oleic acid and erucic acid."
01/01/1998 - "Patients with X-ALD have been treated with Lorenzo's oil, a 4:1 combination of oleic acid and erucic acid, with thrombocytopenia as the main side effect and sometimes leading to a hemorrhagic diathesis. "
03/01/1988 - "There was a significance (P less than 0.05) in the incidence of myocardial necrosis among male rats fed increased levels of erucic acid for one week, but the response was not linear to the increase in dietary erucic acid. "
01/01/1992 - "Although there are no indications of erucic acid toxicity in man, it is known to cause cardiac lipidosis and necrosis in rats. "
07/01/1975 - "There was no correlation between the number of foci of myocardial necrosis and fibrosis and the state of refinement of the oils, but there were generally fewer lesions in rats fed those oils having the lowest levels of erucic acid."
07/01/1975 - "Focal myocardial necrosis and fibrosis occurred in male rats fed rapeseed oils containing different levels of erucic acid for 112 days. "
07/01/1976 - "We have postulated that linolenic acid plays a role in the etiology of cardiac necrosis observed when rats are fed diets containing low erucic acid rapeseed oils."
|2.||Fatty Acids (Saturated Fatty Acids)
|7.||Oleic Acid (Oleate)
|9.||adrenic acid (7,10,13,16-docosatetraenoic acid)
|1.||Bone Marrow Transplantation (Transplantation, Bone Marrow)
|2.||Diet Therapy (Therapy, Diet)