|1.||Won, Shen-Jeu: 5 articles (04/2015 - 03/2002)|
|2.||Lin, Chun-Nan: 4 articles (04/2015 - 03/2002)|
|3.||Liu, Hsiao-Sheng: 3 articles (04/2015 - 10/2005)|
|4.||Su, Chun-Li: 3 articles (04/2015 - 10/2005)|
|5.||Lee, Jenq-Chang: 2 articles (05/2006 - 10/2005)|
|6.||Lan, Sheng-Hui: 1 article (04/2015)|
|7.||Chuang, Jing-Jing: 1 article (04/2015)|
|8.||Chow, Nan-Haw: 1 article (04/2015)|
|9.||Wang, Yi-Wen: 1 article (04/2015)|
|10.||Lee, Chung-Ta: 1 article (04/2015)|
|1.||Colorectal Neoplasms (Colorectal Cancer)
10/01/2005 - "Further study revealed that justicidin A-treated HT-29 and HCT 116 colorectal cancer cells died of apoptosis. "
04/01/2015 - "Justicidin A-induced autophagy flux enhances apoptosis of human colorectal cancer cells via class III PI3K and Atg5 pathway."
10/01/2005 - "The natural product justicidin A, an arylnaphthalide lignan isolated from Justicia procumbens, significantly inhibited the growth of human colorectal cancer cells HT-29 and HCT 116 at day 6 post-treatment. "
10/01/2005 - "Justicidin A decreases the level of cytosolic Ku70 leading to apoptosis in human colorectal cancer cells."
10/01/2005 - "Oral administration of justicidin A was shown to suppress the growth of HT-29 cells transplanted into NOD-SCID mice, suggesting chemotherapeutic potential of justicidin A on colorectal cancer cells."
01/01/2014 - "In this study, five arylnaphthalene lignans including 6'-hydroxy justicidin A (HJA), 6'-hydroxy justicidin B (HJB), justicidin B (JB), chinensinaphthol methyl ether (CME) and Taiwanin E methyl ether (TEME) were isolated from Justicia procumbens and their effects on the proliferation and apoptosis of the human leukemia K562 cell line were investigated then used to assess structure-activity relationships. "
|3.||Joint Diseases (Joint Disease)
03/01/1999 - "In the course of our studies aimed at obtaining new drugs for treatment of bone and joint diseases, chemical modification of the potent bone resorption inhibitors justicidins, was performed and various naphthalene lactones, quinoline lactones and quinoline derivatives bearing an azole moiety at the side chain were prepared. "
12/20/1996 - "In the course of our study aimed at developing new types of DMARDs (disease-modifying antirheumatic drugs), we found that quinoline derivative 1a had a potent anti-inflammatory effect in an adjuvant arthritis (AA) rat model, starting from the potent bone resorption inhibitors justicidins as the lead compounds. "
11/21/2012 - "Here, we identified a new compound 6'-hydroxy justicidin A (JR6) from Justicia procumbens, which showed obvious anti-cancer effects. "
04/01/2015 - "Our previous reports showed that justicidin A (JA), a novel and pure arylnaphthalide lignan isolated from Justicia procumbens, induces apoptosis of human colorectal cancer cells and hepatocellular carcinoma cells, leading to the suppression of both tumor cell growth in NOD-SCID mice. "
03/01/2002 - "The known compounds justicidin A (1), diphyllin (3), and tuberculatin (4) showed potent cytotoxic effects against a number of cancer cells in vitro. "
|1.||Bone Density Conservation Agents
|3.||Antirheumatic Agents (DMARD)
|6.||Ethyl Ether (Ether)
|10.||Caspase 8 (Caspase-8)