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human apolipoprotein E7

a variant of ApoE3 in humans; with two lysine residues replacing glutamic acid at positions 244 and 245 (Glu244-Lys, Glu245-Lys) and defective binding to low density lipoprotein (LDL) receptors; associated with hyperlipidemia and atherosclerosis.
Also Known As:
apolipoprotein E7, human; apo E-7, human; apoE7, human; apolipoprotein E-7, human
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