16,16-Dimethylprostaglandin E2

A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and growth of experimental tumors.

Also Known As:

16,16 Dimethylprostaglandin E2; 16,16-Dimethyl-PGE2; 16,16 Dimethyl PGE2; E2, 16,16-Dimethylprostaglandin; Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (5Z,11alpha,13E,15R)-

Pharmalogical Action Categories:

Anti-Ulcer Agents

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Synthetic Prostaglandins: 823
        Synthetic Prostaglandins E: 6
        16,16-Dimethylprostaglandin E2: 22
Biological Factors: 2472
- Inflammation Mediators: 1113
  - Synthetic Prostaglandins: 823
    - Synthetic Prostaglandins E: 6
      - 16,16-Dimethylprostaglandin E2: 22
  - Autacoids: 276
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Synthetic Prostaglandins: 823
        Synthetic Prostaglandins E: 6
        16,16-Dimethylprostaglandin E2: 22

9- deoxy- 16,16- dimethyl- tetranor- 9- methyleneprostaglandin E2

Bio-Agent Context: Research Results