OP 2507

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13 relevant articles (4 outcomes, 2 trials/studies) found for this Bio-Agent

Description: prostacyclin analog; structure given in first source

Also Known As:

15-(4-propylcyclohexyl)-16,17,18,19,20-pentanor-9-deoxy-9,6-nitrilo-PGF1 methyl ester; OP-2507

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Mineshita, S: 1 article (06/2000)
2.	Honda, Y: 1 article (06/2000)
3.	Miura, A: 1 article (06/2000)
4.	Wang, L M: 1 article (06/2000)
5.	Hao, Y: 1 article (06/2000)
6.	Koike, Y: 1 article (06/2000)

Related Diseases

1.	Ischemia 12/01/2001 - "Compared with the ischemia control group, OP-2507 significantly improved harmful insults following ischemia-reperfusion" 12/01/2001 - "The changes of mean systemic arterial pressure following ischemia-reperfusion have been significantly attenuated by OP- 2507 at both doses" 12/01/1998 - "Compared with ischemia alone, OP-2507 significantly reduced the extent of microcirculatory and hemodynamic derangement following ischemia-reperfusion" 10/01/1992 - "During ischemia, coronary flow in the OP-2507 group increased significantly more than that in the control group" 10/01/1992 - "The hearts were perfused with Krebs-Henseleit bicarbonate (KHB) buffer, and whole heart ischemia was induced by one-way aortic valve for 15 min follows by reperfusion for 30 min. In the treated hearts, OP-2507, 20 ng.ml(-1), was administered to KHB buffer from the beginning to the end of experiment" Order ALL the reference details at left...
2.	Hemorrhagic Shock 04/01/1992 - "The protective effects of the PGI2 analogue, OP-2507 against hypoxic tissue injury were investigated in a 60-70 min acute hemorrhagic shock model in 29 rats" 04/01/1992 - "Protective effects of a PGI2 analogue OP-2507 on hemorrhagic shock in rats--with an evaluation of the metabolic recovery using near-infrared optical monitoring." Order ALL the reference details at left...
3.	Infarction 07/01/1988 - "The results suggested that the protective effect of OP-2507 on regional infarction gave apparent protection against the occurrence of neurological deficits for this compound." Order ALL the reference details at left...
4.	Edema 04/29/1986 - "Protective effects of OP-2507 [15-cis-(4-propylcyclohexyl)-16,17,18,19,20-pentanor-9-deoxy -9 alpha, 6-nitrilo-PGF1 methyl ester] against cerebral anoxia and edema were investigated in a variety of experimental models in mice and rats" 04/29/1986 - "Protective effect of a new prostacyclin analogue OP-2507 against cerebral anoxia and edema in experimental animals." Order ALL the reference details at left...
5.	Brain Hypoxia (Cerebral Hypoxia) 04/29/1986 - "Protective effects of OP-2507 [15-cis-(4-propylcyclohexyl)-16,17,18,19,20-pentanor-9-deoxy -9 alpha, 6-nitrilo-PGF1 methyl ester] against cerebral anoxia and edema were investigated in a variety of experimental models in mice and rats" 04/29/1986 - "Protective effect of a new prostacyclin analogue OP-2507 against cerebral anoxia and edema in experimental animals." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Epoprostenol (Prostacyclin)
2.	Prostaglandins F (PGF)
3.	Oxygen
4.	prostaglandin F1
5.	ozagrel
6.	salicylhydroxamic acid (SHAM)
7.	Phospholipases A2 (Phospholipase A2)
8.	GTP-Binding Proteins (G-Protein)
9.	Eicosanoids
10.	Trypsin

Related Therapies and Procedures

1.	Flowmeters
2.	Transplants (Transplant)
3.	Homologous Transplantation (Allograft)
4.	Ligation
5.	Lasers (Laser)

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