isobutrin

antihepatotoxic principle from Butea monosperma flowers; RN given for (E)-isomer; structure given in first source; also see butrin

Also Known As:

3,4,2',4'-tetrahydroxychalcone-3,4'-diglucoside

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

1.	Mathan, Ganeshan: 1 article (10/2016)
2.	Polachi, Navaneethakrishnan: 1 article (10/2016)
3.	Subramaniyan, Boopathi: 1 article (10/2016)

1.	Liver Neoplasms (Liver Cancer) 10/01/2016 - "The compound isocoreopsin showed significantly greater efficacy in cell death on human colon and liver cancer cell lines (50 μg/mL in HT-29 and 100 μg/mL in HepG2) than butrin (100 μg/mL in HT-29 and 500 μg/mL in HepG2) and isobutrin (80 μg/mL in HT-29 and 150 μg/mL in HepG2). "
2.	Colonic Neoplasms (Colon Cancer) 10/01/2016 - "These results suggest that isocoreopsin, butrin and isobutrin are the important key compounds for the chemoprevention of colon cancer and isocoreopsin can be considered as a promising novel drug."

1.	Chemoprevention