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tris(2-ethylhexyl)phosphate
Also Known As:
2-ethyl-1-hexanol phosphate
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Organophosphorus Compounds: 300
Organophosphates: 1942
tris(2-ethylhexyl)phosphate: 1
Related Diseases
1.
Carcinogenesis
08/01/1984 - "
NTP Toxicology and Carcinogenesis Studies of Tris(2-ethylhexyl)phosphate (CAS No. 78-42-2) In F344/N Rats and B6C3F1 Mice (Gavage Studies).
"
08/01/1984 - "
Two-year toxicology and carcinogenesis studies of tris(2-ethylhexyl)phosphate were conducted by administering the test chemical in corn oil by gavage, 5 days per week for 103 weeks, to groups of 50 male and 50 female F344/N rats and B6C3F1 mice.
"
2.
Pheochromocytoma
08/01/1984 - "
Under the conditions of these studies, a comparison of concurrent and historical controls indicated that there was equivocal evidence of carcinogenicity in male F344/N rats receiving 2,000 and 4,000 mg/kg tris(2-ethylhexyl)phosphate, as evidenced by increased incidences of pheochromocytomas of the adrenal glands.
"
3.
Hyperplasia
08/01/1984 - "
Tris(2-ethylhexyl)phosphate was associated with increased incidences of follicular cell hyperplasia of the thyroid gland in male and female B6C3F1 mice.
"
4.
Hepatocellular Carcinoma (Hepatoma)
08/01/1984 - "
There was some evidence of carcinogenicity in female B6C3F1 mice that received 1,000 mg/kg tris(2-ethylhexyl)phosphate, as shown by an increased incidence of hepatocellular carcinoma.
"
Related Drugs and Biologics
1.
Corn Oil (Oil, Corn)