|1.||Veno, Patricia A: 1 article (01/2003)|
|2.||Ward, William F: 1 article (01/2003)|
|3.||Ts'ao, Chung H: 1 article (01/2003)|
|4.||Small, William: 1 article (01/2003)|
|5.||Molteni, Agostino: 1 article (01/2003)|
|6.||Taylor, JoAnn: 1 article (01/2003)|
|7.||Brizio-Molteni, Loredana: 1 article (01/2003)|
02/01/1989 - "Radiation-induced endothelial dysfunction and fibrosis in rat lung: modification by the angiotensin converting enzyme inhibitor CL242817."
09/01/1986 - "Concomitant CL242817 treatment ameliorated all anatomic manifestations of monocrotaline injury, particularly the right ventricular hypertrophy, pulmonary arterial occlusion, epithelial degeneration, and interstitial fibrosis. "
01/01/2003 - "The ACE inhibitors containing a sulphydril (SH) or thiol radical in their moiety (Captopril and CL242817) seemed to be more effective in controlling fibrosis and the growth of some neoplastic cells than those ACE inhibitors without this thiol radical in their structure, even if the second group of these drugs show in vitro a stronger inhibitory effect on converting enzyme activity. "
|2.||Pulmonary Fibrosis (Hamman Rich Syndrome)
02/01/1989 - "The purpose of this study was to evaluate the angiotensin converting enzyme (ACE) inhibitor CL242817 as a modifier of radiation-induced pulmonary endothelial dysfunction and pulmonary fibrosis in rats sacrificed 2 months after a single dose of 60Co gamma rays (0-30 Gy) to the right hemithorax. "
09/01/1986 - "To determine whether CL242817 also can modify monocrotaline-induced pulmonary injury, male rats were divided into four groups: control; CL242817 (60 mg/kg/day, po); monocrotaline (2.4 mg/kg/day, po); or monocrotaline plus CL242817, and were sacrificed after 6 weeks of continuous treatment. "
09/01/1986 - "Thus CL242817 resembles captopril, both in its ability to ameliorate monocrotaline-induced pulmonary injury in rats, and in many of its side effects."
|4.||Right Ventricular Hypertrophy
|2.||Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)
|3.||Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)
|5.||Hydroxyproline (4 Hydroxyproline)