stinging nettle lectin

MW 8-9kDA; found only in rhizome of above plant; agglutinates erythrocytes nonspecifically irrespective of blood group type & induces the production of gamma-interferon in human lymphocytes

Also Known As:

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Mansouri, Kamran: 1 article (09/2020)
2.	Mostafaie, Ali: 1 article (09/2020)
3.	Rashidbaghan, Azam: 1 article (09/2020)
4.	Yazdani, Yaghoub: 1 article (09/2020)

Related Diseases

1.	Neoplasms (Cancer) 04/01/1995 - "Urtica dioica agglutinin (UDA), a GlcN-Ac-specific lectin from the rhizomes of Urtica dioica, was found to inhibit the binding of (125)I-labelled epidermal growth factor (EGF) to its receptor (EGF-R) on A431 epidermoid cancer cells at concentrations of 500ng/ml to 100μg/ml. The effects of other lectins such as wheat germ agglutinin (WGA), which possesses the same sugar specificity, and the mannose-specific agglutinin from Canavalia ensiformis (Con A) were less pronounced. " 02/01/1996 - "In detail, the binding of Viscum album agglutinin (VAA), Urtica dioica agglutinin (UDA), and of carrier-immobilized N-acetyl-D-glucosamine (GlcNAc), lysoganglioside GM1, estradiol, progesterone, testosterone, and hydrocortisone to native specimens consisting of 46 tumor imprints from surgically treated patients with lung cancer and 74 smears of pleural effusion (PE) cells from cancer or non-cancer patients was studied using fluorescence microscopy with Texas red-labeled streptavidin. "
2.	Infections 04/28/2023 - "Urtica dioica Agglutinin Prevents Rabies Virus Infection in a Muscle Explant Model." 01/01/2022 - "Urtica dioica Agglutinin: A plant protein candidate for inhibition of SARS-COV-2 receptor-binding domain for control of Covid19 Infection."
3.	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 09/30/2020 - "Urtica dioica agglutinin (a plant lectin) has a caspase-dependent apoptosis induction effect on the acute lymphoblastic leukemia cell line."
4.	Pleural Effusion (Pleural Effusions) 02/01/1996 - "In detail, the binding of Viscum album agglutinin (VAA), Urtica dioica agglutinin (UDA), and of carrier-immobilized N-acetyl-D-glucosamine (GlcNAc), lysoganglioside GM1, estradiol, progesterone, testosterone, and hydrocortisone to native specimens consisting of 46 tumor imprints from surgically treated patients with lung cancer and 74 smears of pleural effusion (PE) cells from cancer or non-cancer patients was studied using fluorescence microscopy with Texas red-labeled streptavidin. "
5.	Systemic Lupus Erythematosus (Libman-Sacks Disease) 08/01/1996 - "Urtica dioica agglutinin, a V beta 8.3-specific superantigen, prevents the development of the systemic lupus erythematosus-like pathology of MRL lpr/lpr mice."

Related Drugs and Biologics

1.	Agglutinins
2.	ErbB Receptors (EGF Receptor)
3.	Plant Lectins
4.	Lectins
5.	Streptavidin
6.	Superantigens
7.	Wheat Germ Agglutinins
8.	Testosterone (Sustanon)
9.	Progesterone
10.	Plant Proteins