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5-vinyl-1-arabinofuranosyluracil

RN given refers to beta-(D)-isomer

Also Known As:

VaraU

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleosides: 50
      - Uridine: 1186
        Arabinofuranosyluracil: 37
        5-vinyl-1-arabinofuranosyluracil: 3
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Pyrimidine Nucleosides: 50
    - Uridine: 1186
      - Arabinofuranosyluracil: 37
        5-vinyl-1-arabinofuranosyluracil: 3
  - Arabinonucleosides: 1
    - Arabinofuranosyluracil: 37
      - 5-vinyl-1-arabinofuranosyluracil: 3

Related Diseases

1.	Herpes Simplex Encephalitis (Herpes Encephalitis) 06/01/1987 - "Efficacy of 5-vinyl-1-beta-D-arabinofuranosyluracil (VaraU) against herpes simplex virus type 2 strains in cell cultures and against experimental herpes encephalitis in mice: comparison with acyclovir and foscarnet."
2.	Keratitis 07/01/1988 - "BrVaraU and VaraU have been compared with BrVUdR for their therapeutic effect on acute HSV-1 keratitis in rabbits. " 07/01/1988 - "Evaluation of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil (BrVaraU, VaraU) in the treatment of experimental herpes simplex virus type 1 keratitis in rabbits: comparison with (E)-5-(2-bromovinyl)-2'-deoxyuridine (BrVUdR)."
3.	Infections 03/01/1986 - "Protection of mice from encephalitis and death due to intracerebral (i.c.) infection with a clinical HSV-1 isolate was nearly complete if mice were treated intraperitoneally (i.p.) with two daily doses of VaraU and BrVaraU (100 or 200 mg/kg per day) over a period of 5 or 10 days. "
4.	Encephalitis (Encephalitis, Rasmussen) 03/01/1986 - "Protection of mice from encephalitis and death due to intracerebral (i.c.) infection with a clinical HSV-1 isolate was nearly complete if mice were treated intraperitoneally (i.p.) with two daily doses of VaraU and BrVaraU (100 or 200 mg/kg per day) over a period of 5 or 10 days. "

Related Drugs and Biologics

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3.	Therapeutic Uses
4.	brivudine (brivudin)