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N- solanesyl- N,N'- bis(3,4- dimethoxybenzyl)ethylenediamine

structure given in first source

Also Known As:

SDB-ethylenediamine

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - Diamines: 518
      - Ethylenediamines: 7
        N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine: 5
- Hydrocarbons: 1713
  - Terpenes: 1461
    - N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine: 5

Experts

1.	Gerassimova, Galina K: 1 article (11/2002)
2.	Kakpakova, Eugenia S: 1 article (11/2002)
3.	Nigmatov, Albert G: 1 article (11/2002)
4.	Serebryakov, Edward P: 1 article (11/2002)
5.	Shtil, Alexander A: 1 article (11/2002)
6.	Sidorova, Tatyana A: 1 article (11/2002)
7.	Stavrovskaya, Alla A: 1 article (11/2002)

Related Diseases

1.	Kidney Neoplasms (Kidney Cancer) 11/01/1992 - "In the present study, we studied the sensitizing ability of bis-benzyl-isoquinoline (cepharanthine) and SDB-ethylenediamine (N-1379) in natural MDR kidney cancer cells. "
2.	Neoplasms (Cancer) 06/01/1995 - "The growth of the transplantable nude mouse tumors (SCCRY and SCCTF) was strongly suppressed when BLM was combined with SDB-ethylenediamine. " 11/21/2002 - "Effects of isoprenoid analogues of SDB-ethylenediamine on multidrug resistant tumor cells alone and in combination with chemotherapeutic drugs." 06/01/1995 - "Combined effect of bleomycin (BLM) and N-solanyl-N, N'-bis (3, 4-di-methoxy-benzyl)-ethylenediamine (SDB-ethylenediamine), a synthetic isoprenoid was studied on 3 oral squamous carcinoma cell lines (SCCTF, SCCKN, SCCRY) and clonal cell lines from SCCRY in vitro and on transplantable nude mouse tumors. " 06/01/1995 - "[Combined effect of bleomycin and SDB-ethylenediamine, a synthetic isoprenoid, on oral squamous carcinoma cell lines and transplantable nude mouse tumors]."
3.	Leukemia P388 05/01/1986 - "A cultured subline (P388/ADM) of mouse P388 leukemia resistant to doxorubicin, vinblastine, vincristine, dactinomycin, and daunorubicin became sensitive again when treated with noncytotoxic doses of either of two synthetic isoprenoids: N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine (SDB-ethylenediamine) and N-(p-methylbenzyl)decaprenylamine X HCI (PMB-decaprenylamine). "
4.	Hepatocellular Carcinoma (Hepatoma) 03/01/1990 - "A synthetic isoprenoid, N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine (SDB-ethylenediamine), inhibited the colony formation of multidrug-resistant mutant cell lines derived from Chinese hamster V79 (V79/ADM) and human hepatoma PLC/PRF/5 (PLC/COL) cells to a greater extent than that of the parental cells. "
5.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 06/01/1995 - "Combined effect of bleomycin (BLM) and N-solanyl-N, N'-bis (3, 4-di-methoxy-benzyl)-ethylenediamine (SDB-ethylenediamine), a synthetic isoprenoid was studied on 3 oral squamous carcinoma cell lines (SCCTF, SCCKN, SCCRY) and clonal cell lines from SCCRY in vitro and on transplantable nude mouse tumors. " 06/01/1995 - "[Combined effect of bleomycin and SDB-ethylenediamine, a synthetic isoprenoid, on oral squamous carcinoma cell lines and transplantable nude mouse tumors]."

Related Drugs and Biologics

1.	Benzylisoquinolines
2.	cepharanthine
3.	Terpenes (Terpenoids)
4.	N- solanesyl- N,N'- bis(3,4- dimethoxybenzyl)ethylenediamine
5.	Vincristine (Oncovin)
6.	Vinblastine (Vinblastine Sulfate)
7.	Doxorubicin (Adriamycin)
8.	Daunorubicin (Cerubidine)
9.	Dactinomycin (Actinomycin)
10.	Bleomycin (Blenoxane)