butaprost

highly selective prostaglandin receptor agonist; structure given in first source

Also Known As:

15-deoxy-16-hydroxy-17-cyclobutylprostaglandin E1 methyl ester; DOH-CB-PGE1; TR 4979; TR-4979; Cyclopentaneheptanoic acid, 3-hydroxy-2-(4-hydroxy-4-(1-propylcyclobutyl)-1-butenyl)-5-oxo-, methyl ester, (1R-(1alpha,2beta(1E,4R*),3alpha))-

Networked: 19 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Picado, César: 2 articles (07/2020 - 12/2012)
2.	Torres, Rosa: 2 articles (07/2020 - 12/2012)
3.	de Mora, Fernando: 2 articles (07/2020 - 12/2012)
4.	Chen, Jing: 2 articles (01/2019 - 09/2008)
5.	Kang, Kui Dong: 2 articles (05/2010 - 07/2009)
6.	Al-Kandery, Al-Shaimaa A: 1 article (11/2021)
7.	El-Hashim, Ahmed Z: 1 article (11/2021)
8.	Rao, Muddanna S: 1 article (11/2021)
9.	Plaza, Judith: 1 article (07/2020)
10.	Urbano, Adrián: 1 article (07/2020)

Related Diseases

1.	Ureteral Obstruction 01/01/2019 - "We studied the anti-fibrotic efficacy of butaprost using Madin-Darby Canine Kidney (MDCK) cells, mice that underwent unilateral ureteral obstruction and human precision-cut kidney slices. " 01/01/2019 - "In addition, treatment with 4 mg/kg/day butaprost attenuated the development of fibrosis in mice that underwent unilateral ureteral obstruction surgery, as illustrated by a reduction in the gene and protein expression of α-smooth muscle actin, FN and collagen 1A1. "
2.	Glaucoma 01/01/2017 - "Given the significance of wound healing modulation in blebs, butaprost's inhibitory effect on subconjunctival Tenon's fibroblasts may be beneficial in managing postoperative scarring in glaucoma surgery."
3.	Cicatrix (Scar) 01/01/2017 - "Butaprost effectively reduces the subconjunctival scarring response. " 01/01/2017 - "Anti-scarring effects of butaprost on human subconjunctival Tenon's fibroblasts." 01/01/2017 - "Given the significance of wound healing modulation in blebs, butaprost's inhibitory effect on subconjunctival Tenon's fibroblasts may be beneficial in managing postoperative scarring in glaucoma surgery."
4.	Blister (Bulla) 01/01/2017 - "Given the significance of wound healing modulation in blebs, butaprost's inhibitory effect on subconjunctival Tenon's fibroblasts may be beneficial in managing postoperative scarring in glaucoma surgery."
5.	Hyperalgesia 07/01/1994 - "Butaprost(EP2) induced hyperalgesia at doses higher than 50 ng kg-1.5. " 07/01/1994 - "Butaprost (EP2), 11-deoxy PGE1 (EP2 = EP3), MB 28767 (EP3), and cicaprost (prostaglandin I2 (IP-) receptor) induced allodynia, but with much lower scores. " 04/17/1995 - "Intrathecal injection of butaprost (10 ng/mouse), an EP2 agonist, induced hyperalgesia, and this hyperalgesia was blocked by D-AP5, 7-Cl-KynA, ketamine, and MK801, similar to that induced by 10 ng of PGE2. " 10/01/1997 - "6. PGE2, PGF2alpha, butaprost (an EP2 agonist) and cicaprost (a PGI receptor agonist) did not affect the nociceptin-induced allodynia. "

Related Drugs and Biologics

1.	Dinoprostone (PGE2)
2.	Retinaldehyde (Retinal)
3.	Prostaglandins E
4.	cicaprost
5.	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
6.	Cyclooxygenase 2 (Cyclooxygenase-2)
7.	Natriuretic Agents
8.	Prostaglandin E Receptors (Prostaglandin E Receptor)
9.	Dizocilpine Maleate (Dizocilpine)
10.	Dinoprost

Related Therapies and Procedures

1.	Spinal Injections