|1.||Shen, Jian: 3 articles (10/2013 - 11/2010)|
|2.||Zhou, Lin: 3 articles (10/2013 - 11/2010)|
|3.||Wei, Shaohua: 3 articles (10/2013 - 11/2010)|
|4.||Zhou, Jiahong: 3 articles (10/2013 - 11/2010)|
|5.||Olivo, Malini: 3 articles (01/2006 - 01/2002)|
|6.||Korbelik, Mladen: 2 articles (01/2012 - 11/2009)|
|7.||Madiyalakan, Ragupathy: 2 articles (01/2012 - 12/2010)|
|8.||Woo, Thomas: 2 articles (01/2012 - 12/2010)|
|9.||Ali, Seyed Mohamed: 2 articles (12/2002 - 01/2002)|
|10.||Olivo, M: 2 articles (12/2001 - 09/2001)|
11/01/2010 - "In vitro studies have demonstrated the active uptake of amorphous formulation of hypocrellin A into the mitochondria of tumor cells. "
08/01/2012 - "Hypocrellin A is an efficient photodynamic agent against many tumor cells and viruses. "
11/01/2010 - "Compared with Tween-80 micelle embedded hypocrellin A, low dark-toxicity but similar light-toxicity of the amorphous one to drug impregnated tumor cells was observed. "
09/01/2001 - "The molecular mechanisms of tumor cell death induction by Hypocrellin A and B are poorly understood. "
06/01/1994 - "The results showed that, in the presence of 3.66 mumol/L hypocrellin A, illumination of HeLa cells with visible light, the morphology was changed and the microvilli on the cells were disappeared; the proliferation of the cells decreased with increasing irradiated dose and this effect seemed more sensitive in tumor cells than in normal cells; the increased population of cycle cells at S phase but decreased at G1 phase were observed by FCM; the photodamage effect of hypocrellin A induced the sparse distribution of cytoplasmic microtubles and almost disappearance of the fluorescence intensity of MTOC, they were observed in HeLa cells as shown by immunofluoresent microscopy. "
|2.||Photosensitivity Disorders (Photodermatitis)
06/01/1994 - "[An experimental study on photosensitization of cultured human cells with hypocrellin A]."
07/01/1998 - "Hypocrellin A photosensitization involves an intracellular pH decrease in 3T3 cells."
06/01/1994 - "All the aforesaid results indicated that photosensitization of hypocrellin A inhibits cells growth, resulting from the damage in cell membrane and cytoskeleton and S phase delay of the cell cycle."
02/01/1992 - "DNA damage induced by hypocrellin-A photosensitization."
09/01/1989 - "The primary reaction of photosensitization of Hypocrellin A (HA) has been studied by using techniques of ESR, spin-trapping and spin-counteraction. "
|3.||Phototoxic Dermatitis (Phototoxicity)
05/03/2010 - "Toxicity and phototoxicity of Hypocrellin A on malignant human cell lines, evidence of a synergistic action of photodynamic therapy with Imatinib mesylate."
12/01/2000 - "Hypocrellin and hypericin-induced phototoxicity of HL-60 cells: apoptosis or necrosis?"
12/01/2002 - "Hypocrellin compounds were selected as potential photosensitizers for PDT owing to their high quantum yields of singlet oxygen (1O2), and facility for site-directed chemical modification to enhance phototoxicity, pharmacokinetics, solubility, and light absorption in the red spectral region, among other properties. "
11/01/1997 - "The titers of vesicular stomatitis virus (VSV) and human immunodeficiency virus type 1 (HIV-1), both of which are enveloped viruses, were reduced upon illumination with hypocrellin A in a concentration-dependent manner, whereas canine parvovirus, a nonenveloped virus, was not killed. "
|5.||Colorectal Neoplasms (Colorectal Cancer)
|1.||Photosensitizing Agents (Photosensitizers)
|4.||Mercaptoethanol (2 Mercaptoethanol)
|6.||2-Propanol (Isopropyl Alcohol)
|9.||polyvinylidene fluoride (PVDF)
|1.||Photochemotherapy (Photodynamic Therapy)